Abstract Ischemia/reperfusion (I/R) is a critical risk factor for acute kidney injury (AKI). Recent
studies provided evidence that tubular epithelial cells (TEC)-associated inflammation …

Kidney in diabetic state is more sensitive to ischemic acute kidney injury (AKI). However, the
underlying mechanisms remain unclear. Herein, we examined the impact of diabetes …

Iodinated contrast media serves as a direct causative factor of acute kidney injury (AKI) and
is involved in the progression of cellular dysfunction and apoptosis. Emerging evidence …

The NOD-like receptor family, pyrin domain containing-3 (NLRP3) inflammasome has been
implicated in renal inflammation and fibrosis. However, the biological function of …

Growing evidence has shown that NLRP3 inflammasome activation promotes the
development of tubulointerstitial inflammation and progression of renal injury. We previously …

Abstract Background/aims The Nod-like receptor protein-3 (NLRP3) inflammasome
signalling pathway is involved in the inflammatory reaction of myocardial ischaemia …

Inflammation significantly contributes to the progression of chronic kidney disease (CKD).
Inflammasome-dependent cytokines, such as IL-1β and IL-18, play a role in CKD, but their …

Nod-like receptor protein 3 (NLRP3), as an inflammatory regulator, has been implicated in
acute kidney injury (AKI). Failed recovery after AKI can lead to chronic kidney disease …

Ischemia and reperfusion (I/R) causes a reduction in arterial blood supply to tissues,
followed by the restoration of perfusion and consequent reoxygenation. The reestablishment …

Increasing evidence suggests that inflammation and apoptosis are involved in the
development of acute myocardial ischemia (AMI). Nucleotide-binding oligomerization …