Clinical and molecular mechanisms favoring cancer initiation and progression in diabetic patients
Cancer incidence and mortality are higher among diabetic patients. This review examines
the mechanisms, both general and site-specific, for this increase. Hyperglycemia and …
the mechanisms, both general and site-specific, for this increase. Hyperglycemia and …
[HTML][HTML] Diabetes and cancer: Associations, mechanisms, and implications for medical practice
CX Xu, HH Zhu, YM Zhu - World journal of diabetes, 2014 - ncbi.nlm.nih.gov
Both diabetes mellitus and cancer are prevalent diseases worldwide. It is evident that there
is a substantial increase in cancer incidence in diabetic patients. Epidemiologic studies …
is a substantial increase in cancer incidence in diabetic patients. Epidemiologic studies …
Obesity and cancer, a case for insulin signaling
Y Poloz, V Stambolic - Cell death & disease, 2015 - nature.com
Obesity is a worldwide epidemic, with the number of overweight and obese individuals
climbing from just over 500 million in 2008 to 1.9 billion in 2014. Type 2 diabetes (T2D) …
climbing from just over 500 million in 2008 to 1.9 billion in 2014. Type 2 diabetes (T2D) …
Obesity related hyperinsulinaemia and hyperglycaemia and cancer development
S Becker, L Dossus, R Kaaks - Archives of physiology and …, 2009 - Taylor & Francis
Excess body weight in combination with physical inactivity is a major determinant for the
development of insulin resistance with associated hyperglycaemia and hyperinsulinaemia …
development of insulin resistance with associated hyperglycaemia and hyperinsulinaemia …
Metabolic health, insulin, and breast cancer: why oncologists should care about insulin
LD Yee, JE Mortimer, R Natarajan, EC Dietze… - Frontiers in …, 2020 - frontiersin.org
Studies investigating the potential link between adult pre-menopausal obesity [as measured
by body mass index (BMI)] and triple-negative breast cancer have been inconsistent. Recent …
by body mass index (BMI)] and triple-negative breast cancer have been inconsistent. Recent …
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
EE Calle, R Kaaks - Nature Reviews Cancer, 2004 - nature.com
The prevalence of obesity is rapidly increasing globally. Epidemiological studies have
associated obesity with a range of cancer types, although the mechanisms by which obesity …
associated obesity with a range of cancer types, although the mechanisms by which obesity …
Burden of cancer attributable to obesity, type 2 diabetes and associated risk factors
A López-Suárez - Metabolism, 2019 - Elsevier
Overweight and obesity constitute a global pandemic with devastating consequences that
affect> 2 billion people. Obesity plays a central role in morbidity and mortality of diseases of …
affect> 2 billion people. Obesity plays a central role in morbidity and mortality of diseases of …
[HTML][HTML] Obesity, diabetes, and increased cancer progression
DS Kim, PE Scherer - Diabetes & metabolism journal, 2021 - synapse.koreamed.org
Rates of obesity and diabetes have increased significantly over the past decades and the
prevalence is expected to continue to rise further in the coming years. Many observations …
prevalence is expected to continue to rise further in the coming years. Many observations …
Hyperinsulinaemia in cancer
EJ Gallagher, D LeRoith - Nature Reviews Cancer, 2020 - nature.com
Elevated circulating insulin levels are frequently observed in the setting of obesity and early
type 2 diabetes, as a result of insensitivity of metabolic tissues to the effects of insulin. Higher …
type 2 diabetes, as a result of insensitivity of metabolic tissues to the effects of insulin. Higher …
[PDF][PDF] Obesity and its impact on breast cancer: tumor incidence, recurrence, survival, and possible interventions
JA Ligibel, HD Strickler - American Society of Clinical Oncology …, 2013 - ascopubs.org
A positive association between obesity and the risk of incident postmenopausal breast
cancer has been consistently observed in epidemiologic studies. Although most studies of …
cancer has been consistently observed in epidemiologic studies. Although most studies of …