Cancer incidence and mortality are higher among diabetic patients. This review examines
the mechanisms, both general and site-specific, for this increase. Hyperglycemia and …

Both diabetes mellitus and cancer are prevalent diseases worldwide. It is evident that there
is a substantial increase in cancer incidence in diabetic patients. Epidemiologic studies …

Obesity is a worldwide epidemic, with the number of overweight and obese individuals
climbing from just over 500 million in 2008 to 1.9 billion in 2014. Type 2 diabetes (T2D) …

Excess body weight in combination with physical inactivity is a major determinant for the
development of insulin resistance with associated hyperglycaemia and hyperinsulinaemia …

Studies investigating the potential link between adult pre-menopausal obesity [as measured
by body mass index (BMI)] and triple-negative breast cancer have been inconsistent. Recent …

The prevalence of obesity is rapidly increasing globally. Epidemiological studies have
associated obesity with a range of cancer types, although the mechanisms by which obesity …

Overweight and obesity constitute a global pandemic with devastating consequences that
affect> 2 billion people. Obesity plays a central role in morbidity and mortality of diseases of …

Rates of obesity and diabetes have increased significantly over the past decades and the
prevalence is expected to continue to rise further in the coming years. Many observations …

Elevated circulating insulin levels are frequently observed in the setting of obesity and early
type 2 diabetes, as a result of insensitivity of metabolic tissues to the effects of insulin. Higher …

A positive association between obesity and the risk of incident postmenopausal breast
cancer has been consistently observed in epidemiologic studies. Although most studies of …