Principles and applications of multidimensional protein identification technology

AC Paoletti, B Zybailov… - Expert review of proteomics, 2004 - Taylor & Francis
Multidimensional chromatography coupled to tandem mass spectrometry is an emerging
technique for the analysis of proteomes and is rapidly being implemented by many …

Proteomic analysis by multidimensional protein identification technology

D Nedelkov, RW Nelson, L Florens… - New and Emerging …, 2006 - Springer
Multidimensional chromatography coupled to mass spectrometry is an emerging technique
for the analysis of complex protein mixtures. One approach in this general category …

Analysis of protein composition using multidimensional chromatography and mass spectrometry

AJ Link, MP Washburn - Current Protocols in Protein Science, 2014 - Wiley Online Library
Multidimensional liquid chromatography of peptides produced by protease digestion of
complex protein mixtures followed by tandem mass spectrometry can be coupled with …

Generation and analysis of multidimensional protein identification technology datasets

SK Swanson, L Florens, MP Washburn - Mass Spectrometry of Proteins …, 2009 - Springer
Systems that couple two dimensional liquid chromatography (LC/LC) with tandem mass
spectrometry are widely used in modern proteomics. One such system, multidimensional …

Multidimensional protein identification technology

K Lohrig, D Wolters - Proteomics: Methods and Protocols, 2009 - Springer
Over the past years, large-scale analysis of proteomes gained increased interest to obtain a
fast but nevertheless comprehensive overview about cellular protein content. While a …

Utilisation of proteomics datasets generated via multidimensional protein identification technology (MudPIT)

MP Washburn - Briefings in Functional Genomics, 2004 - academic.oup.com
Technological developments in proteomics have had a dramatic impact on biology in recent
years. One of these developments—named multidimensional protein identification …

Proteomic analysis with integrated multiple dimensional liquid chromatography/mass spectrometry based on elution of ion exchange column using pH steps

J Dai, CH Shieh, QH Sheng, H Zhou… - Analytical …, 2005 - ACS Publications
A novel integrated multidimensional liquid chromatography (IMDL) method is demonstrated
for the separation of peptide mixtures by two-dimensional HPLC coupled with ion trap mass …

Multidimensional separations for protein/peptide analysis in the post-genomic era

H Liu, D Lin, JR Yates III - Biotechniques, 2002 - Taylor & Francis
Proteomics is the study of all or part of the protein complement of genes in an organism,
often involving the analysis of complex protein/peptide samples. Such complex samples are …

Multi-dimensional liquid chromatography in proteomics—a review

X Zhang, A Fang, CP Riley, M Wang, FE Regnier… - Analytica chimica …, 2010 - Elsevier
Proteomics is the large-scale study of proteins, particularly their expression, structures and
functions. This still-emerging combination of technologies aims to describe and characterize …

[PDF][PDF] MudPIT: multidimensional protein identification technology

CM Delahunty, JR Yates 3rd - Biotechniques, 2007 - ufpel.edu.br
Multidimensional protein identification technology (MudPIT)(1) developed as a method to
analyze the highly complex samples necessary for large-scale proteome analysis by …