Genetic variations in human papillomavirus and cervical cancer outcomes

JS Rader, SW Tsaih, D Fullin… - … journal of cancer, 2019 - Wiley Online Library
Cervical cancer is driven by persistent infection of human papillomavirus (HPV), which is
influenced by HPV type and intratypic variants, yet the impact of HPV type and intratypic …

High Levels of Within-Host Variations of Human Papillomavirus 16 E1/E2 Genes in Invasive Cervical Cancer

Y Hirose, M Yamaguchi-Naka, M Onuki… - Frontiers in …, 2020 - frontiersin.org
Human papillomavirus type 16 (HPV16) is the most common HPV genotype found in
invasive cervical cancer (ICC). Recent comprehensive genomics studies of HPV16 have …

The intersection of HPV epidemiology, genomics and mechanistic studies of HPV-mediated carcinogenesis

L Mirabello, MA Clarke, CW Nelson, M Dean… - 2018 - mdpi.com
Of the~ 60 human papillomavirus (HPV) genotypes that infect the cervicovaginal epithelium,
only 12–13 “high-risk” types are well-established as causing cervical cancer, with HPV16 …

Human papillomavirus genomics: Understanding carcinogenicity

CW Nelson, L Mirabello - Tumour Virus Research, 2023 - Elsevier
Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …

HPV16 Intratypic Variants in Head and Neck Cancers: A North American Perspective

SF Gameiro, MY Salnikov, PYF Zeng, JW Barrett… - Viruses, 2023 - mdpi.com
Human papillomavirus (HPV) is the major causative agent for cervical and many head and
neck cancers (HNCs). HPVs randomly acquire single nucleotide polymorphisms (SNPs) that …

[HTML][HTML] Variants in human papillomavirus receptor and associated genes are associated with type-specific HPV infection and lesion progression of the cervix

J Zou, Z Cao, J Zhang, T Chen, S Yang, Y Huang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Human papillomavirus (HPV) infects cervical epithelial cells through cellular membrane
receptors, and then induces the initiation and progression of cervical cancer. Single …

Lineages of oncogenic human papillomavirus types other than type 16 and 18 and risk for cervical intraepithelial neoplasia

LF Xi, M Schiffman, LA Koutsky… - Journal of the …, 2014 - academic.oup.com
Background Data on clinical outcomes of infection with variants of oncogenic human
papillomavirus (HPV) types other than HPV16 and HPV18 are rare. We investigated …

A population-based prospective study of carcinogenic human papillomavirus variant lineages, viral persistence, and cervical neoplasia

M Schiffman, AC Rodriguez, Z Chen, S Wacholder… - Cancer research, 2010 - AACR
Human papillomavirus (HPV) types differ profoundly in cervical carcinogenicity. For the most
carcinogenic type HPV16, variant lineages representing further evolutionary divergence …

Mutational landscape and intra-host diversity of human papillomavirus type 16 long control region and E6 variants in cervical samples

N Escobar-Escamilla, BE González-Martínez… - Archives of …, 2019 - Springer
Abstract Human papillomavirus genotype 16 (HPV16) is the most frequent high-risk HPV
(HR-HPV) identified in cervical precursor lesions and cervical cancer (CC) worldwide. The …

Independent prognostic role of human papillomavirus genotype in cervical cancer

D Hang, M Jia, H Ma, J Zhou, X Feng, Z Lyu, J Yin… - BMC Infectious …, 2017 - Springer
Background Although the correlation of HPV genotype with cervical precursor lesions and
invasive cancer has been confirmed, the role of HPV genotype in cervical cancer prognosis …