Long-term modification of cortical synapses improves sensory perception

RC Froemke, I Carcea, AJ Barker, K Yuan… - Nature …, 2013 - nature.com
Synapses and receptive fields of the cerebral cortex are plastic. However, changes to
specific inputs must be coordinated within neural networks to ensure that excitability and …

Scaling down of balanced excitation and inhibition by active behavioral states in auditory cortex

M Zhou, F Liang, XR Xiong, L Li, H Li, Z Xiao… - Nature …, 2014 - nature.com
Cortical sensory processing is modulated by behavioral and cognitive states. How this
modulation is achieved by changing synaptic circuits remains largely unknown. In awake …

A synaptic memory trace for cortical receptive field plasticity

RC Froemke, MM Merzenich, CE Schreiner - Nature, 2007 - nature.com
Receptive fields of sensory cortical neurons are plastic, changing in response to alterations
of neural activity or sensory experience,,,,,,,,,,,. In this way, cortical representations of the …

Cortical network reorganization guided by sensory input features

MP Kilgard, PK Pandya, ND Engineer, R Moucha - Biological cybernetics, 2002 - Springer
Sensory experience alters the functional organization of cortical networks. Previous studies
using behavioral training motivated by aversive or rewarding stimuli have demonstrated that …

The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex

F Zhu, S Elnozahy, J Lawlor, KV Kuchibhotla - Nature neuroscience, 2023 - nature.com
Cholinergic basal forebrain (CBF) signaling exhibits multiple timescales of activity with
classic slow signals related to brain and behavioral states and fast, phasic signals reflecting …

Dynamics of auditory cortical activity during behavioural engagement and auditory perception

I Carcea, MN Insanally, RC Froemke - Nature Communications, 2017 - nature.com
Behavioural engagement can enhance sensory perception. However, the neuronal
mechanisms by which behavioural states affect stimulus perception remain poorly …

Tactile frequency discrimination is enhanced by circumventing neocortical adaptation

S Musall, W Von Der Behrens, JM Mayrhofer… - Nature …, 2014 - nature.com
Neocortical responses typically adapt to repeated sensory stimulation, improving sensitivity
to stimulus changes, but possibly also imposing limitations on perception. For example, it is …

Adaptive, behaviorally gated, persistent encoding of task-relevant auditory information in ferret frontal cortex

JB Fritz, SV David, S Radtke-Schuller, P Yin… - Nature …, 2010 - nature.com
Top-down signals from frontal cortex are thought to be important in cognitive control of
sensory processing. To explore this interaction, we compared activity in ferret frontal cortex …

Defining cortical frequency tuning with recurrent excitatory circuitry

B Liu, GK Wu, R Arbuckle, HW Tao, LI Zhang - Nature neuroscience, 2007 - nature.com
Neurons in the recipient layers of sensory cortices receive excitatory input from two major
sources: the feedforward thalamocortical and recurrent intracortical inputs. To address their …

Basal forebrain activation enhances cortical coding of natural scenes

M Goard, Y Dan - Nature neuroscience, 2009 - nature.com
The nucleus basalis of the basal forebrain is an essential component of the
neuromodulatory system controlling the behavioral state of an animal and it is thought to be …