Apolipoprotein AI (apo AI) is the major protein of high-density lipoprotein (HDL). Using
radioimmunoassay, we measured plasma apo AI levels in 1,880 individuals in 283 …

For quantitative traits associated with risk to complex diseases, such as heart disease, single
major locus models are likely to be too simplistic. Currently, researchers have begun to use …

Knapp RG, Schreiner PJ, Sutherland SE, Keil JE, Gilbert GE, Klein RL, Hames C, Tyroler
HA. Serum lipoprotein (a) levels in elderly black and white men in the Charleston Heart …

The Lp (a) antigen resides in a polypeptide chain that is attached to apolipoprotein B (apoB)
by a disulfide bridge. Recently, cDNA for this polypeptide chain (frequently referred to as the …

Lp (a) levels are genetically determined and remain stable without major changes
throughout lives. However, when an individual's Lp (a) levels are observed over a one-year …

Distributions of plasma lipoprotein (a)(Lp [a]) concentrations exhibit marked interracial
differences. Apolipoprotein (a)(apo [a]), the unique constituent of Lp (a), is highly …

Elevated concentrations of lipoprotein (a)(Lp [a]) in plasma are associated with premature
coronary heart disease (CHD). Lp (a) levels are largely determined by alleles at the …

Initially, lipoprotein (a)[Lp (a)] was believed to be a genetic variant of lipoprotein (Lp)-B.
Because its lipid moiety is almost identical to LDL, Lp (a) has been deliberately considered …

Abstract Lipoprotein (a)[Lp (a)] is a quantitative genetic trait in human plasma associated
with atherothrombotic disease. The major determinant of Lp (a) concentration is the …

Concentration of lipoprotein (a) in plasma is inherited in an autosomal co-dominant manner
and its high concentration leads to atherothrombotic disease. Nucleotide sequence analysis …