BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications
M Xing - Endocrine reviews, 2007 - academic.oup.com
In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has
received enthusiastic investigation, and significant progress has been made toward …
received enthusiastic investigation, and significant progress has been made toward …
BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications
KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
Papillary thyroid cancer (PTC) is the most common endocrine malignancy, accounting for 85–
90% of all thyroid cancers. Genetic alternations involving the mitogen-activated protein …
90% of all thyroid cancers. Genetic alternations involving the mitogen-activated protein …
BRAF mutation in thyroid cancer
M Xing - Endocrine-related cancer, 2005 - erc.bioscientifica.com
Genetic alteration is the driving force for thyroid tumorigenesis and progression, based upon
which novel approaches to the management of thyroid cancer can be developed. A recent …
which novel approaches to the management of thyroid cancer can be developed. A recent …
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer
M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
Context: Use of BRAF mutation in papillary thyroid cancer (PTC) has the potential to improve
risk stratification of this cancer. Objective: The objective of the study was to investigate the …
risk stratification of this cancer. Objective: The objective of the study was to investigate the …
Prognostic utility of BRAF mutation in papillary thyroid cancer
M Xing - Molecular and cellular endocrinology, 2010 - Elsevier
Papillary thyroid cancer (PTC) is a common endocrine malignancy that frequently harbors
the oncogenic T1799A BRAF mutation. As a novel prognostic molecular marker, this …
the oncogenic T1799A BRAF mutation. As a novel prognostic molecular marker, this …
Clinical implications of BRAF mutation in thyroid carcinoma
Significant progress has recently been made in the clinical management of papillary thyroid
carcinoma. The accuracy of diagnosis and prognostic stratification of this type of carcinoma …
carcinoma. The accuracy of diagnosis and prognostic stratification of this type of carcinoma …
Clinicopathologic Implications of the BRAFV600E Mutation in Papillary Thyroid Cancer: A Subgroup Analysis of 3130 Cases in a Single Center
JY Lim, SW Hong, YS Lee, BW Kim, CS Park… - Thyroid, 2013 - liebertpub.com
Background: The BRAF mutation has been shown to be associated with aggressive
clinicopathologic characteristics of papillary thyroid cancer (PTC). However, several studies …
clinicopathologic characteristics of papillary thyroid cancer (PTC). However, several studies …
BRAF mutation is not predictive of long‐term outcome in papillary thyroid carcinoma
LE Henke, JD Pfeifer, C Ma, SM Perkins… - Cancer …, 2015 - Wiley Online Library
The BRAF mutation occurs commonly in papillary thyroid carcinoma (PTC). Previous
investigations of its utility to predict recurrence‐free survival (RFS) and disease‐specific …
investigations of its utility to predict recurrence‐free survival (RFS) and disease‐specific …
BRAF T1796A Transversion Mutation in Various Thyroid Neoplasms
A high prevalence of activating mutation of the B type Raf kinase (BRAF) gene was recently
reported in papillary thyroid cancer (PTC). However, the frequency of this mutation in several …
reported in papillary thyroid cancer (PTC). However, the frequency of this mutation in several …
Association of BRAF V600E mutation with poor clinicopathological outcomes in 500 consecutive cases of papillary thyroid carcinoma
C Lupi, R Giannini, C Ugolini, A Proietti… - The Journal of …, 2007 - academic.oup.com
Context: Because very few studies have examined the correlation between BRAF mutations
and clinicopathological features of papillary thyroid carcinoma (PTC), we analyzed here a …
and clinicopathological features of papillary thyroid carcinoma (PTC), we analyzed here a …
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