RNase1 as a potential mediator of remote ischaemic preconditioning for cardioprotection
HA Cabrera-Fuentes, B Niemann… - European Journal of …, 2015 - academic.oup.com
OBJECTIVES Remote ischaemic preconditioning (RIPC) is a non-invasive and virtually cost-
free strategy for protecting the heart against acute ischaemia–reperfusion injury (IRI). We …
free strategy for protecting the heart against acute ischaemia–reperfusion injury (IRI). We …
Interaction of δ and κ opioid receptors with adenosine A1 receptors mediates cardioprotection by remote ischemic preconditioning
H Surendra, RJ Diaz, K Harvey, M Tropak… - Journal of molecular and …, 2013 - Elsevier
Multiple initiatives are underway to harness the clinical benefits of remote ischemic
preconditioning (rIPC) based on applying non-invasive, brief, intermittent limb …
preconditioning (rIPC) based on applying non-invasive, brief, intermittent limb …
Resistance exercise mediates remote ischemic preconditioning by limiting cardiac eNOS uncoupling
MNS Santana, DS Souza, R Miguel-dos-Santos… - Journal of molecular and …, 2018 - Elsevier
Background Currently viewed as a complementary non-pharmacological intervention for
preventing cardiac disorders, long-term aerobic training produces cardioprotection through …
preventing cardiac disorders, long-term aerobic training produces cardioprotection through …
Cardioprotection by remote ischemic preconditioning exhibits a signaling pattern different from local ischemic preconditioning
NM Heinen, VE Pütz, JI Görgens, R Huhn, Y Grüber… - Shock, 2011 - journals.lww.com
Remote ischemic preconditioning (RIPC) and local ischemic preconditioning (IPC) protect
the myocardium from subsequent ischemia/reperfusion (I/R) injury. In this study, the …
the myocardium from subsequent ischemia/reperfusion (I/R) injury. In this study, the …
The innate immune response in reperfused myocardium
L Timmers, G Pasterkamp, VC de Hoog… - Cardiovascular …, 2012 - academic.oup.com
One of the major therapeutic challenges in the arena of interventional cardiology is to design
strategies aimed at reducing myocardial tissue damage after myocardial infarction. In …
strategies aimed at reducing myocardial tissue damage after myocardial infarction. In …
Remote ischemic postconditioning protects against renal ischemia/reperfusion injury by activation of T-LAK-cell-originated protein kinase (TOPK)/PTEN/Akt signaling …
Background Recent clinical and animal studies suggested that remote limb ischemic
postconditioning (RIPostC) can invoke potent cardioprotection or neuroprotection. However …
postconditioning (RIPostC) can invoke potent cardioprotection or neuroprotection. However …
Remote preconditioning provides potent cardioprotection via PI3K/Akt activation and is associated with nuclear accumulation of β-catenin
J Li, W Xuan, R Yan, MB Tropak… - Clinical …, 2011 - portlandpress.com
rIPC [remote IPC (ischaemic preconditioning)] has been shown to invoke potent myocardial
protection in animal studies and recent clinical trials. Although the important role of PI3K …
protection in animal studies and recent clinical trials. Although the important role of PI3K …
Remote ischaemic conditioning: cardiac protection from afar
V Sivaraman, JMJ Pickard, DJ Hausenloy - Anaesthesia, 2015 - Wiley Online Library
For patients with ischaemic heart disease, remote ischaemic conditioning may offer an
innovative, non‐invasive and virtually cost‐free therapy for protecting the myocardium …
innovative, non‐invasive and virtually cost‐free therapy for protecting the myocardium …
SR9009 administered for one day after myocardial ischemia-reperfusion prevents heart failure in mice by targeting the cardiac inflammasome
CJ Reitz, FJ Alibhai, TN Khatua, M Rasouli… - Communications …, 2019 - nature.com
Reperfusion of patients after myocardial infarction (heart attack) triggers cardiac
inflammation that leads to infarct expansion and heart failure (HF). We previously showed …
inflammation that leads to infarct expansion and heart failure (HF). We previously showed …
Cardioprotective efficacy of limb remote ischaemic preconditioning in rats: discrepancy between a meta-analysis and a three-centre in vivo study
Aims Remote ischaemic preconditioning (RIPC) is a robust cardioprotective intervention in
preclinical studies. To establish a working and efficacious RIPC protocol in our laboratories …
preclinical studies. To establish a working and efficacious RIPC protocol in our laboratories …