Molecular mechanisms and pathways involved in bovine embryonic genome activation and their regulation by alternative in vivo and in vitro culture conditions
Understanding gene expression patterns in response to altered environmental conditions at
different time points of the preimplantation period would improve our knowledge on …
different time points of the preimplantation period would improve our knowledge on …
[HTML][HTML] Single-cell RNA sequencing reveals developmental heterogeneity of blastomeres during major genome activation in bovine embryos
I Lavagi, S Krebs, K Simmet, A Beck… - Scientific reports, 2018 - nature.com
Embryonic development is initially controlled by maternal RNAs and proteins stored in the
oocyte, until gene products gradually generated by the embryo itself take over. Major …
oocyte, until gene products gradually generated by the embryo itself take over. Major …
[HTML][HTML] Association between the morphokinetics of in-vitro-derived bovine embryos and the transcriptomic profile of the derived blastocysts
The time-lapse system is a non-invasive method that enables a continuous evaluation
through embryo development. Here, we examined the association between the …
through embryo development. Here, we examined the association between the …
Genome activation in bovine embryos: review of the literature and new insights from RNA sequencing experiments
A Graf, S Krebs, M Heininen-Brown… - Animal reproduction …, 2014 - Elsevier
Maternal-to-embryonic transition (MET) is the period in early embryonic development when
maternal RNAs and proteins stored in the oocyte are gradually degraded and transcription …
maternal RNAs and proteins stored in the oocyte are gradually degraded and transcription …
[HTML][HTML] Developmental and molecular correlates of bovine preimplantation embryos
H Sagirkaya, M Misirlioglu, A Kaya, NL First… - …, 2006 - rep.bioscientifica.com
Expression of embryonic genes is altered in different culture conditions, which influence
developmental potential both during preimplantation and fetal development. The objective of …
developmental potential both during preimplantation and fetal development. The objective of …
Differential gene expression profile in bovine blastocysts resulting from hyperglycemia exposure during early cleavage stages
GLM Cagnone, I Dufort, C Vigneault… - Biology of …, 2012 - academic.oup.com
To understand the compromised survival of embryos derived from assisted reproductive
techniques, transcriptome survey of early embryonic development has shown the impact of …
techniques, transcriptome survey of early embryonic development has shown the impact of …
Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo
Bovine embryos can be generated by in vitro fertilization or somatic nuclear transfer;
however, these differ from their in vivo counterparts in many aspects and exhibit a higher …
however, these differ from their in vivo counterparts in many aspects and exhibit a higher …
Dynamics of global transcriptome in bovine matured oocytes and preimplantation embryos
M Misirlioglu, GP Page, H Sagirkaya… - Proceedings of the …, 2006 - National Acad Sciences
Global activation of the embryonic genome is the most critical event in early mammalian
development. After fertilization, a rich supply of maternal proteins and RNAs support …
development. After fertilization, a rich supply of maternal proteins and RNAs support …
Fine mapping of genome activation in bovine embryos by RNA sequencing
A Graf, S Krebs, V Zakhartchenko… - Proceedings of the …, 2014 - National Acad Sciences
During maternal-to-embryonic transition control of embryonic development gradually
switches from maternal RNAs and proteins stored in the oocyte to gene products generated …
switches from maternal RNAs and proteins stored in the oocyte to gene products generated …
Large-scale transcriptional analysis of bovine embryo biopsies in relation to pregnancy success after transfer to recipients
A El-Sayed, M Hoelker, F Rings… - Physiological …, 2006 - journals.physiology.org
The purpose of this work is to address the relationship between transcriptional profile of
embryos and the pregnancy success based on gene expression analysis of blastocyst …
embryos and the pregnancy success based on gene expression analysis of blastocyst …
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