[HTML][HTML] Marine bisindole alkaloid: A potential apoptotic inducer in human cancer cells
S Salucci, S Burattini, F Buontempo… - European Journal of …, 2018 - ncbi.nlm.nih.gov
Marine organisms such as corals, sponges and tunicates produce active molecules which
could represent a valid starting point for new drug development processes. Among the …
could represent a valid starting point for new drug development processes. Among the …
Morpho‐functional analyses reveal that changes in the chemical structure of a marine bisindole alkaloid alter the cytotoxic effect of its derivatives
S Burattini, M Battistelli, M Verboni… - Microscopy …, 2022 - Wiley Online Library
bis (6‐bromo‐1 H‐indol‐3‐yl) ethanamine, a marine bisindole alkaloid, showed anticancer
property in several tumor cell lines thanks to the presence of a 3, 3′‐diindolylmethane …
property in several tumor cell lines thanks to the presence of a 3, 3′‐diindolylmethane …
Marine-inspired bis-indoles possessing antiproliferative activity against breast cancer; design, synthesis, and biological evaluation
Diverse indoles and bis-indoles extracted from marine sources have been identified as
promising anticancer leads. Herein, we designed and synthesized novel bis-indole series …
promising anticancer leads. Herein, we designed and synthesized novel bis-indole series …
Indole-3-carbinol and 3, 3′-diindolylmethane induce apoptosis in human prostate cancer cells
M Nachshon-Kedmi, S Yannai, A Haj… - Food and Chemical …, 2003 - Elsevier
Cruciferous vegetables contain glucobrassicin which, during metabolism, yields indole-3-
carbinol (I3C). In a low pH environment I3C is converted into polymeric products, among …
carbinol (I3C). In a low pH environment I3C is converted into polymeric products, among …
Indole-3-carbinol inhibits nasopharyngeal carcinoma
W Zhu, W Li, G Yang, Q Zhang, M Li… - International journal of …, 2010 - journals.sagepub.com
This study explored the effects of indole-3-carbinol on the proliferation of human
nasopharyngeal carcinoma, both in vitro and in vivo, and the underlying mechanisms in …
nasopharyngeal carcinoma, both in vitro and in vivo, and the underlying mechanisms in …
Marine bromophenol bis (2, 3-dibromo-4, 5-dihydroxybenzyl) ether, induces mitochondrial apoptosis in K562 cells and inhibits topoisomerase I in vitro
M Liu, W Zhang, J Wei, L Qiu, X Lin - Toxicology letters, 2012 - Elsevier
Bis (2, 3-dibromo-4, 5-dihydroxybenzyl) ether (BDDE) is a marine bromophenol compound
derived from marine algae. Previous reports have shown that BDDE possesses cytotoxic …
derived from marine algae. Previous reports have shown that BDDE possesses cytotoxic …
[HTML][HTML] Purified brominated indole derivatives from Dicathais orbita induce apoptosis and cell cycle arrest in colorectal cancer cell lines
Dicathais orbita is a large Australian marine gastropod known to produce bioactive
compounds with anticancer properties. In this research, we used bioassay guided …
compounds with anticancer properties. In this research, we used bioassay guided …
Induction of apoptosis in human breast cancer cells by nimbolide through extrinsic and intrinsic pathway
We aimed to investigate the cytotoxic effects of nimbolide, a limonoid present in leaves and
flowers of the neem tree (Azadirachta indica) on human breast cancer cells. The molecular …
flowers of the neem tree (Azadirachta indica) on human breast cancer cells. The molecular …
Indole-3-carbinol enhances ultraviolet B-induced apoptosis by sensitizing human melanoma cells
DS Kim, YM Jeong, SI Moon, SY Kim, SB Kwon… - Cellular and Molecular …, 2006 - Springer
Indole-3-carbinol (I3C) has been found to act against several types of cancer, while
ultraviolet B (UVB) is known to induce the apoptosis of human melanoma cells. Here, we …
ultraviolet B (UVB) is known to induce the apoptosis of human melanoma cells. Here, we …
Inhibition of nuclear translocation of nuclear factor-κB contributes to 3, 3′-diindolylmethane-induced apoptosis in breast cancer cells
KMW Rahman, FH Sarkar - Cancer research, 2005 - AACR
Abstract Dietary indole-3-carbinol (I3C), a natural compound present in vegetables of the
genus Brassica, showed clinical benefits and caused apoptosis in breast cancer cells. Our …
genus Brassica, showed clinical benefits and caused apoptosis in breast cancer cells. Our …