Renal fibrosis: novel insights into mechanisms and therapeutic targets

P Boor, T Ostendorf, J Floege - Nature Reviews Nephrology, 2010 - nature.com
Renal fibrosis is the common end point of virtually all progressive kidney diseases. Renal
fibrosis should not be viewed as a simple and uniform'scar', but rather as a dynamic system …

Mechanisms of tubulointerstitial fibrosis

M Zeisberg, EG Neilson - Journal of the American Society of …, 2010 - journals.lww.com
The pathologic paradigm for renal progression is advancing tubulointerstitial fibrosis.
Whereas mechanisms underlying fibrogenesis have grown in scope and understanding in …

Pathophysiological mechanisms of renal fibrosis: a review of animal models and therapeutic strategies

A Nogueira, MJ Pires, PA Oliveira - In vivo, 2017 - iv.iiarjournals.org
Chronic kidney disease (CKD) is a long-term condition in which the kidneys do not work
correctly. It has a high prevalence and represents a serious hazard to human health and …

Cellular and molecular mechanisms of renal fibrosis

Y Liu - Nature Reviews Nephrology, 2011 - nature.com
Renal fibrosis, particularly tubulointerstitial fibrosis, is the common final outcome of almost
all progressive chronic kidney diseases. Renal fibrosis is also a reliable predictor of …

Cellular and molecular mechanisms of kidney fibrosis

S Djudjaj, P Boor - Molecular aspects of medicine, 2019 - Elsevier
Renal fibrosis is the final pathological process common to any ongoing, chronic kidney
injury or maladaptive repair. It is considered as the underlying pathological process of …

Mechanisms of renal fibrosis

BD Humphreys - Annual review of physiology, 2018 - annualreviews.org
Tubulointerstitial fibrosis is a chronic and progressive process affecting kidneys during aging
and in chronic kidney disease (CKD), regardless of cause. CKD and renal fibrosis affect half …

Cellular and molecular pathways that lead to progression and regression of renal fibrogenesis

H Okada, R Kalluri - Current molecular medicine, 2005 - ingentaconnect.com
Renal fibrosis is a common consequence and often a central feature of all the progressive
renal diseases that lead to end-stage renal failure. In comparison to wound healing, during …

Renal fibrosis: insights into pathogenesis and treatment

AM El Nahas, EC Muchaneta-Kubara… - The international journal …, 1997 - Elsevier
The progression of chronic renal failure is characterised histologically by
glomerulosclerosis, tubulointerstitial fibrosis and vascular sclerosis. Recent research has …

Novel insights into renal fibrosis

F Eitner, J Floege - Current opinion in nephrology and …, 2003 - journals.lww.com
Novel insights into renal fibrosis : Current Opinion in Nephrology and Hypertension Novel
insights into renal fibrosis : Current Opinion in Nephrology and Hypertension Log in or Register …

Renal fibrosis: an update

M Zeisberg, F Strutz, GA Müller - Current opinion in nephrology …, 2001 - journals.lww.com
Tubulointerstitial fibrosis invariably accompanies the course of chronic renal failure towards
end-stage renal disease. Tubular epithelial cells, the predominant cell type in the …