NO/redox imbalance, endothelial dysfunction and MPO activity 2.1. Oxidative/nitrosative
stress: the role of radicals 3. Redox mechanisms in blood vessels: sources of ROS 3.1 …

Production of reactive oxygen species (ROS) occurs as a byproduct of numerous signaling
pathways and mitochondrial respiration; ROS, themselves, are signaling molecules …

Adaptation of the heart to intrinsic and external stress involves complex modifications at the
molecular and cellular levels that lead to tissue remodeling, functional and metabolic …

Heart failure is the major cause of hospitalization, morbidity and mortality worldwide.
Previous experimental and clinical studies have suggested that there is an increased …

There is not too much success in the antioxidant treatment of heart deceases in humans.
However a new approach is now developed that suggests that depending on their structures …

The notion of oxidative stress has changed over the past decades from the idea of being a
phenomenon involved exclusively with oxidative damage to a more contemporary concept …

Heart failure constitutes a major cardiovascular health hazard worldwide. It afflicts over 1%
of the general population and nearly 1 in 10 of the elderly. Chronic heart failure (CHF) also …

Oxidative stress (OS) is mediated by reactive oxygen species (ROS), which in
cardiovascular and other disease states, damage DNA, lipids, proteins, other cellular and …

There is growing evidence that the altered production and/or spatiotemporal distribution of
reactive oxygen and nitrogen species creates oxidative and/or nitrosative stresses in the …

The morbidity and mortality from cardiovascular diseases (CVD) remain high. Metabolic
diseases such as obesity, hyperlipidemia, diabetes mellitus (DM), non-alcoholic fatty liver …