Giant invasive pituitary prolactinoma with falsely low serum prolactin: the significance of 'hook effect'

M Fleseriu, M Lee, MM Pineyro, M Skugor… - Journal of Neuro …, 2006 - Springer
The authors report a case of a patient with giant, invasive skull base tumor extending to the
parasellar area discovered incidentally during the work-up for decreased memory. The …

Falsely low serum prolactin in two cases of invasive macroprolactinoma

C Schöfl, B Schöfl-Siegert, JH Karstens, M Bremer… - Pituitary, 2002 - Springer
The differential diagnosis of tumors at the base of the skull comprises meningiomas,
neurinomas, gliomas, metastatic carcinomas, chordomas, epidermoids, and pituitary …

Giant prolactinomas presenting as skull base tumors

G Minniti, ML Jaffrain-Rea, A Santoro, V Esposito… - Surgical neurology, 2002 - Elsevier
BACKGROUND: Prolactinomas invading the skull base are rare, and could easily be
confused with skull base tumors of nonpituitary origin. CASE DESCRIPTION: We report a …

Treatments of multi-invasive giant prolactinoma

MY Yang, CC Shen, WL Ho - Journal of Clinical Neuroscience, 2004 - Elsevier
We present a 68-year-old male patient with an exceptionally aggressive tumour which
invaded to the skull base, cavernous sinus, nasopharynx, sphenoid sinus, pituitary fossa …

Giant pituitary prolactinoma with falsely low serum prolactin: the pitfall of the" high-dose hook effect": case report

AL Barkan, WF Chandler - Neurosurgery, 1998 - journals.lww.com
OBJECTIVE AND IMPORTANCE: We present a case of a giant prolactinoma with a falsely
low serum prolactin concentration determined by a two-site chemiluminometric assay …

Prolactinomas in men masquerading as invasive skull base tumours

RJ Cook, D Uttley, PR Wilkins, DJ Archer… - British journal of …, 1994 - Taylor & Francis
Four giant prolactin-secreting tumours invading the skull base are described. All of them
occurred in men. The presenting features were sufficiently diverse to be clinically …

What causes a prolactinoma to be aggressive or to become a pituitary carcinoma?

J Phillips, HE East, SE French, E Melcescu… - Hormones, 2012 - Springer
INTRODUCTION Malignant prolactinoma is an exceedingly rare endocrine tumor and
cannot be diagnosed on histological grounds alone. Similarly to other neuroendocrine …

[HTML][HTML] Delayed presentation of late-onset cerebrospinal fluid rhinorrhoea following dopamine agonist therapy for giant prolactinoma

JK Prague, CL Ward, OG Mustafa… - … & Metabolism Case …, 2014 - edm.bioscientifica.com
Therapeutic shrinkage of prolactinomas with dopamine agonists achieves clinical benefit but
can expose fistulae that have arisen as a result of bony erosion of the sella floor and anterior …

Giant invasive prolactinoma: a case report and review of nine further cases

JRE DAVIS, MC SHEPPARD… - QJM: An International …, 1990 - academic.oup.com
Very large prolactinomas are rare and may be difficult to treat. We present the report of a
patient with an exceptionally aggressive tumour which extended outside the skull and …

Obstructive hydrocephalus and intracranial hypertension caused by a giant macroprolactinoma. Prompt response to medical treatment

P Scarone, M Losa, P Mortini, M Giovanelli - Journal of Neuro-oncology, 2006 - Springer
Patients with large prolactin (PRL)-secreting pituitary adenoma often have symptoms due to
varying degree of hypopituitarism and/or mass effect on visual structures, while presentation …