Functional domain mapping of peroxin Pex19p: interaction with Pex3p is essential for function and translocation

Y Matsuzono, T Matsuzaki, Y Fujiki - Journal of cell science, 2006 - journals.biologists.com
The peroxin Pex19p functions in peroxisomal membrane assembly. Here we mapped
functional domains of human Pex19p comprising 299 amino acids. Pex19p mutants deleted …

The peroxin Pex3p initiates membrane assembly in peroxisome biogenesis

K Ghaedi, S Tamura, K Okumoto… - Molecular biology of …, 2000 - Am Soc Cell Biol
Rat cDNA encoding a 372-amino-acid peroxin was isolated, primarily by functional
complementation screening, using a peroxisome-deficient Chinese hamster ovary cell …

Molecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p …

K Okumoto, I Abe, Y Fujiki - Journal of Biological Chemistry, 2000 - ASBMB
The three peroxin genes, PEX12, PEX2, and PEX10, encode peroxisomal integral
membrane proteins with RING finger at the C-terminal part and are responsible for human …

The membrane biogenesis peroxin Pex16p: topogenesis and functional roles in peroxisomal membrane assembly

M Honsho, T Hiroshige, Y Fujiki - Journal of Biological Chemistry, 2002 - ASBMB
Previously we isolated human PEX16encoding 336-amino acid-long peroxin Pex16p and
showed that its dysfunction was responsible for Zellweger syndrome of complementation …

Functional regions of the peroxin Pex19 necessary for peroxisome biogenesis

G Agrawal, HH Shang, ZJ Xia, S Subramani - Journal of Biological …, 2017 - ASBMB
The peroxins Pex19 and Pex3 play an indispensable role in peroxisomal membrane protein
(PMP) biogenesis, peroxisome division, and inheritance. Pex19 plays multiple roles in these …

A new yeast peroxin, Pex36, a functional homolog of mammalian PEX16, functions in the ER-to-peroxisome traffic of peroxisomal membrane proteins

JC Farré, K Carolino, V Stasyk, OG Stasyk… - Journal of molecular …, 2017 - Elsevier
Peroxisomal membrane proteins (PMPs) traffic to peroxisomes by two mechanisms: direct
insertion from the cytosol into the peroxisomal membrane and indirect trafficking to …

The role of conserved PEX3 regions in PEX19‐binding and peroxisome biogenesis

F Schmidt, D Dietrich, R Eylenstein, Y Groemping… - Traffic, 2012 - Wiley Online Library
The human peroxins PEX3 and PEX19 are essential for peroxisome biogenesis. They
mediate the import of membrane proteins as well as the de novo formation of peroxisomes …

[PDF][PDF] Peroxisome membrane biogenesis: the stage is set

W Schliebs, WH Kunau - Current biology, 2004 - cell.com
Pex3p and Pex19p are key players in the post-translational import of peroxisomal
membrane proteins. New data suggest that these peroxins act in tandem, Pex19p as a …

Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19

F Schmidt, N Treiber, G Zocher, S Bjelic… - Journal of biological …, 2010 - ASBMB
The human peroxins PEX3 and PEX19 play a central role in peroxisomal membrane
biogenesis. The membrane-anchored PEX3 serves as the receptor for cytosolic PEX19 …

Characterization of the interaction between recombinant human peroxin Pex3p and Pex19p: identification of TRP-104 IN Pex3p as a critical residue for the interaction

Y Sato, H Shibata, H Nakano, Y Matsuzono… - Journal of biological …, 2008 - ASBMB
Proteins required for peroxisome biogenesis are termed peroxins. The peroxin Pex3p is a
peroxisomal membrane protein (PMP), involved in peroxisomal membrane biogenesis. It …