We have identified ScPex18p and ScPex21p, two novel S. cerevisiae peroxins required for
protein targeting via the PTS2 branch of peroxisomal biogenesis. Targeting by this pathway …

We cloned a human cDNA encoding an isoform of the peroxin Pex11p, termed Pex11pβ, by
screening of human liver cDNA library using as a probe human EST-derived,∼ 300 bp-long …

Peroxin 2 (PEX2) is a 35-kDa integral peroxisomal membrane protein with two
transmembrane regions and a zinc RING domain within its cytoplasmically exposed C …

Peroxisomes are independent organelles found in virtually all eukaryotic cells. Genetic
studies have identified more than 20 PEX genes that are required for peroxisome …

The conserved CaaX box peroxin Pex19p is known to be modified by farnesylation. The
possible involvement of this lipid modification in peroxisome biogenesis, the degree to …

Pex7p, the peroxisome-targeting signal type 2 (PTS2) receptor, transports PTS2 proteins to
peroxisomes from the cytosol. We here established a cell-free Pex7p translocation system …

Peroxisomal matrix protein import requires PEX12, an integral peroxisomal membrane
protein with a zinc ring domain at its carboxy terminus. Mutations in human PEX12 result in …

The Saccharomyces cerevisiae pex17-1 mutant was isolated from a screen to identify
mutants defective in peroxisome biogenesis. pex17-1 and pex17 null mutants fail to import …

Peroxisomes are ubiquitous organelles involved in diverse metabolic processes, most
notably the metabolism of lipids and the detoxification of reactive oxygen species …

Peroxisomes are components of virtually all eukaryotic cells. While much is known about
peroxisomal matrix protein import, our understanding of how peroxisomal membrane …