Ubiquitination of mammalian Pex5p, the peroxisomal import receptor

AF Carvalho, MP Pinto, CP Grou, IS Alencastre… - Journal of Biological …, 2007 - ASBMB
Protein translocation across the peroxisomal membrane requires the concerted action of
numerous peroxins. One central component of this machinery is Pex5p, the cycling receptor …

Pichia pastoris Pex14p, a phosphorylated peroxisomal membrane protein, is part of a PTS–receptor docking complex and interacts with many peroxins

MA Johnson, WB Snyder, J Lin Cereghino, M Veenhuis… - Yeast, 2001 - Wiley Online Library
The peroxisomal protein import machinery plays a central role in the assembly of this
organelle in all eukaryotes. Genes encoding components of this machinery, termed peroxins …

Characterization of the mammalian peroxisomal import machinery: Pex2p, Pex5p, Pex12p, and Pex14p are subunits of the same protein assembly

C Reguenga, MEM Oliveira, AMM Gouveia… - Journal of Biological …, 2001 - ASBMB
Although many of the proteins involved in the biogenesis of the mammalian peroxisome
have already been identified, our knowledge of the architecture of all this machinery is still …

Self-interaction of human Pex11pβ during peroxisomal growth and division

NA Bonekamp, S Grille, MJ Cardoso, M Almeida… - PLoS …, 2013 - journals.plos.org
Pex11 proteins are involved in membrane elongation and division processes associated
with the multiplication of peroxisomes. Human Pex11pβ has recently been linked to a new …

Dynamics of the peroxisomal import cycle of PpPex20p: ubiquitin-dependent localization and regulation

S Léon, L Zhang, WH McDonald, J Yates III… - The Journal of cell …, 2006 - rupress.org
We characterize the peroxin PpPex20p from Pichia pastoris and show its requirement for
translocation of PTS2 cargoes into peroxisomes. PpPex20p docks at the peroxisomal …

A PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway

TA Rodrigues, IS Alencastre, T Francisco… - … and cellular biology, 2014 - Taylor & Francis
Peroxisomal matrix proteins are synthesized on cytosolic ribosomes and transported to the
organelle by shuttling receptors. Matrix proteins containing a type 1 signal are carried to the …

Sorting pathway and molecular targeting signals for the Arabidopsis peroxin 3

JE Hunt, RN Trelease - Biochemical and biophysical research …, 2004 - Elsevier
Peroxin 3 (Pex3p) has been identified and characterized as a peroxisomal membrane
protein in yeasts and mammals. We identified two putative homologs in Arabidopsis …

Domain mapping of human PEX5 reveals functional and structural similarities to Saccharomyces cerevisiae Pex18p and Pex21p

G Dodt, D Warren, E Becker, P Rehling… - Journal of Biological …, 2001 - ASBMB
PEX5 functions as an import receptor for proteins with the type-1 peroxisomal targeting
signal (PTS1). Although PEX5 is not involved in the import of PTS2-targeted proteins in …

The peroxisomal matrix import of Pex8p requires only PTS receptors and Pex14p

C Ma, U Schumann, N Rayapuram… - Molecular biology of the …, 2009 - Am Soc Cell Biol
Pichia pastoris (Pp) Pex8p, the only known intraperoxisomal peroxin at steady state, is
targeted to peroxisomes by either the peroxisomal targeting signal (PTS) type 1 or PTS2 …

Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p

S Tamura, S Yasutake, N Matsumoto, Y Fujiki - Journal of Biological …, 2006 - ASBMB
Two AAA peroxins, Pex1p and Pex6p, are encoded by PEX1 and PEX6, the causal genes
for peroxisome biogenesis disorders of complementation group 1 (CG1) and CG4 …