Indolizidine Alkaloids: Prospective Lead Molecules in Medicinal Chemistry

V Sharma, R Kamal, D Kumar… - Current Traditional …, 2021 - ingentaconnect.com
Natural products are well known for their therapeutic properties. The primary reason for their
therapeutic effectiveness is the presence of secondary plant metabolites like alkaloids …

Cytisine-type alkaloids and flavonoids from the rhizomes of Sophora tonkinensis

QM Pan, GJ Zhang, RZ Huang, YM Pan… - Journal of asian …, 2016 - Taylor & Francis
A new cytisine-type alkaloid,(−)-N-hexanoylcytisine (1), and a new isoflavan,(3 S, 4 R)-4-
hydroxy-7, 4′-dimethoxyisoflavan 3′-O-β-d-glucopyranoside (2), along with 10 known …

Perspectives on the Role of Isoliquiritigenin in Cancer

KL Wang, YC Yu, SM Hsia - Cancers, 2021 - mdpi.com
Simple Summary Isoliquiritigenin (ISL), a natural bioactive compound with a chalcone
structure, demonstrates high antitumor efficacy. This review presents a summary of the latest …

Quinoline alkaloids against neglected tropical diseases

R Musiol, K Malarz, J Mularski - Current Organic Chemistry, 2017 - ingentaconnect.com
Background: The quinoline moiety has been reported to be a privileged structure due to its
presence in many drugs. It appears in alkaloids and natural products such as quinine …

Transcriptome analysis of nine tissues to discover genes involved in the biosynthesis of active ingredients in Sophora flavescens

R Han, H Takahashi, M Nakamura… - Biological and …, 2015 - jstage.jst.go.jp
Sophora flavescens AITON (kurara, 苦参) has long been used to treat various diseases.
Although several research findings revealed the biosynthetic pathways of its characteristic …

Bioactivity diversity and functional mechanism of tetrahydroisoquinoline alkaloids

CJ Liu, DY Liu, L Xiang - Yao xue xue bao= Acta Pharmaceutica …, 2010 - europepmc.org
Tetrahydroisoquinoline alkaloids distributed widely in the nature and some have a broad
application in clinic. More attention has been paid in recent years on this type of alkaloid …

Systematic analysis of chemical profiles of Sophorae tonkinensis Radix et Rhizoma in vitro and in vivo using UPLC‐Q‐TOF‐MSE

W Yuan, Z Huang, S Xiao, Y Zhang… - Biomedical …, 2022 - Wiley Online Library
Abstract Sophorae tonkinensis Radix et Rhizoma (S. tonkinensis) has been recorded as a
'poisonous' Chinese herbal medicine in Chinese Pharmacopoeia 2020. The clinical reaction …

Anti-cancer activity of new benzyl isoquinoline alkaloid from Saudi plant Annona squamosa

AM Al-Ghazzawi - BMC chemistry, 2019 - Springer
Two alkaloids, belonging to benzylisoquinoline alkaloids, were isolated from Annona
squamosa. One of these alkaloids, 6, 7-dimethoxy-1-(α-hydroxy-4-methoxybenzyl)-2-methyl …

Isoquinoline alkaloids isolated from Glaucium corniculatum var. corniculatum and Glaucium grandiflorum subsp. refractum var. torquatum with bioactivity studies

T Kusman Saygi, N Tan, GÖ Alim Toraman… - Pharmaceutical …, 2023 - Taylor & Francis
Abstract Context The genus Glaucium Mill., one of the important Papaveraceae family
plants, is rich in isoquinoline alkaloids and distributed worldwide. Objective Isolation and …

Medicinal significance, pharmacological activities, and analytical aspects of solasodine: A concise report of current scientific literature

K Patel, RB Singh, DK Patel - Journal of Acute Disease, 2013 - Elsevier
Alkaloids are well known phytoconstituents for their diverse pharmacological properties.
Alkaloids are found in all plant parts like roots, stems, leaves, flowers, fruits and seeds …