Antinociceptive effect of agonists microinjected into the anterior pretectal nucleus of the rat

WA Prado - Brain research, 1989 - Elsevier
Electrical stimulation at many sites within the pretectal complex and adjacent structures of
the rat dorsomedial thalamus yields antinociception. It is documented that no other site in …

The antinociception evoked by anterior pretectal nucleus stimulation is partially dependent upon ventrolateral medullary neurones

MG Terenzi, H Rees, SJS Morgan, GA Foster… - Pain, 1991 - Elsevier
Electrical stimulation (35 μA rms/15 s) of the anterior pretectal nucleus (APtN) inhibits the
spinal reflex of the tail-flick (TF) to noxious heat in unanaesthetised rats. APtN stimulation …

Participation of brainstem nuclei in the pronociceptive effect of lesion or neural block of the anterior pretectal nucleus in a rat model of incisional pain

CF Villarreal, VAV Kina, WA Prado - Neuropharmacology, 2004 - Elsevier
The anterior pretectal nucleus (APtN) participates in nociceptive process and controls spinal
nociceptive inputs, and its integrity reduces the severity of the responses to persistent injury …

5-hydroxytryptamine 1A (5-HT1A) but not 5-HT3 receptor is involved in mediating the nucleus submedius 5-HT-evoked antinociception in the rat

DQ Xiao, JX Zhu, JS Tang, H Jia - Brain research, 2005 - Elsevier
Our previous studies have indicated that the thalamic nucleus submedius (Sm) is involved in
modulation of nociception as part of an ascending component of an endogenous analgesic …

GABAergic modulation mediates antinociception produced by serotonin applied into thalamic nucleus submedius of the rat

DQ Xiao, JX Zhu, JS Tang, H Jia - Brain research, 2005 - Elsevier
Our previous studies have indicated that the thalamic nucleus submedius (Sm) is involved in
modulation of nociception as part of an ascending component of an endogenous analgesic …

Roles of the rostroventromedial medulla and the spinal 5-HT1A receptor in descending antinociception induced by motor cortex stimulation in the neuropathic rat

H Viisanen, A Pertovaara - Neuroscience letters, 2010 - Elsevier
Electric stimulation of the primary motor cortex (M1) has been effective in suppressing pain-
related responses in neuropathic as well as healthy control animals. We studied whether the …

Antinociception induced by stimulating the anterior pretectal nucleus in two models of pain in rats

CF Villarreal, VAV Kina… - Clinical and experimental …, 2004 - Wiley Online Library
This study examined whether different parts of the rat anterior pretectal nucleus (APtN) may
be involved in the spinal control of brief (tail flick test) or persistent (surgical incision of the …

Analgesia induced by 2-or 100-Hz electroacupuncture in the rat tail-flick test depends on the anterior pretectal nucleus

ML Silva, JRT Silva, WA Prado - Life Sciences, 2013 - Elsevier
Aims The anterior pretectal nucleus (APtN) and electroacupuncture (EA) activate
descending mechanisms to modulate nociceptive inputs in the spinal dorsal horn. This study …

Role of dopamine D2-like receptors within the ventral tegmental area and nucleus accumbens in antinociception induced by lateral hypothalamus stimulation

M Moradi, M Yazdanian, A Haghparast - Behavioural brain research, 2015 - Elsevier
Several lines of evidence have shown that stimulation of the lateral hypothalamus (LH) can
induce antinociception. It has been indicated that hypothalamic orexinergic neurons send …

The integrity of the anterior pretectal nucleus and dorsolateral funiculus is necessary for electroacupuncture-induced analgesia in the rat tail-flick test

ML Silva, JRT Silva, WA Prado - European Journal of Pain, 2010 - Elsevier
Previous studies have indicated that the anterior pretectal nucleus (APtN) is implicated in
pathways that descend through the dorsolateral funiculus (DLF) to modulate nociceptive …