Intrinsic connections within the pedunculopontine tegmental nucleus are critical to the elaboration of post‐ictal antinociception

EC Mazzei‐Silva, RC de Oliveira, TDA Garcia… - Synapse, 2014 - Wiley Online Library
This study investigated the intrinsic connections of a key‐structure of the endogenous pain
inhibitory system, the pedunculopontine tegmental nucleus (PPTN), in post‐ictal …

5-Hydroxytryptamine2A/2C receptors of nucleus raphe magnus and gigantocellularis/paragigantocellularis pars α reticular nuclei modulate the unconditioned fear …

R de Oliveira, RC de Oliveira… - Behavioural Brain …, 2017 - Elsevier
The electrical stimulation of the dorsolateral columns of the periaquedutal grey matter
(dlPAG) or deep layers of the superior colliculus (dlSC) evokes defensive behaviours …

Descending mechanisms activated by the anterior pretectal nucleus initiate but do not maintain neuropathic pain in rats

AC Rossaneis, K Genaro, QM Dias… - … Journal of Pain, 2015 - Wiley Online Library
Background The anterior pretectal nucleus (APtN) activates descending mechanisms of pain
control. This study evaluated whether the APtN also controls neuropathic pain in rats …

Modulation of persistent nociceptive inputs in the anterior pretectal nucleus of the rat

CF Villarreal, WA Prado - Pain, 2007 - Elsevier
The anterior pretectal nucleus (APtN) participates in nociceptive and antinociceptive
mechanisms. Drugs were injected into the ventral APtN to evaluate how intrinsic …

Serotonergic neurotransmission in the dorsal raphe nucleus recruits in situ 5-HT2A/2C receptors to modulate the post-ictal antinociception

RL Freitas, GS Bassi, AM de Oliveira… - Experimental neurology, 2008 - Elsevier
The post-ictal immobility syndrome is followed by a significant increase in the nociceptive
thresholds in animals and humans. The aim of this study was to assess the involvement of …

Activation of ascending antinociceptive system by vagal afferent input as revealed in the nucleus ventralis posteromedialis

Y Nishikawa, N Koyama, Y Yoshida, T Yokota - Brain research, 1999 - Elsevier
Thalamic nociceptive neurons receiving afferent input from the tooth pulp (TP) were
recorded from the nucleus ventralis posteromedialis proper (VPM) in cats anesthetized with …

Stimulation of the lateral hypothalamus produces antinociception mediated by 5-HT1A, 5-HT1B and 5-HT3 receptors in the rat spinal cord dorsal horn

JE Holden, EN Farah, Y Jeong - Neuroscience, 2005 - Elsevier
The lateral hypothalamus is part of an efferent system that modifies pain at the spinal cord
dorsal horn, but the mechanisms by which lateral hypothalamus-induced antinociception …

[HTML][HTML] Antinociceptive effect of stimulating the occipital or retrosplenial cortex in rats

GM Reis, QM Dias, JWS Silveira, F Del Vecchio… - The Journal of …, 2010 - Elsevier
A role for the occipital or retrosplenial cortex in nociceptive processing has not been
demonstrated yet, but connections from these cortices to brain structures involved in …

Differential effects of opioid receptors in nucleus submedius and anterior pretectal nucleus in mediating electroacupuncture analgesia in the rat.

JX Zhu, JS Tang, H Jia - Sheng Li Xue Bao:[acta Physiologica …, 2004 - europepmc.org
Previous studies have indicated that the thalamic nucleus submedius (Sm) and the anterior
pretectal nucleus (APtN) are involved in the descending modulation of nociception. The aim …

The role of the anterior pretectal nucleus in pain modulation: A comprehensive review

K Genaro, WA Prado - European Journal of Neuroscience, 2021 - Wiley Online Library
Descending pain modulation involves multiple encephalic sites and pathways that range
from the cerebral cortex to the spinal cord. Behavioral studies conducted in the 1980s …