Phase II study of a fixed dose-rate infusion of gemcitabine associated with erlotinib in advanced pancreatic cancer
Purpose To evaluate the feasibility, toxicity and efficacy of the combination regimen
consisting of gemcitabine-FDR infusion plus erlotinib, in ACP patients. Methods Forty-two …
consisting of gemcitabine-FDR infusion plus erlotinib, in ACP patients. Methods Forty-two …
A phase II trial of Erlotinib in combination with gemcitabine and cisplatin in advanced pancreatic cancer
IG Hwang, JS Jang, SY Oh, S Lee, HC Kwon… - Investigational new …, 2012 - Springer
Background Gemcitabine has been recognized as a standard chemotherapy in advanced
pancreas cancer (APC). We conducted a phase II study of a triple combination regimen …
pancreas cancer (APC). We conducted a phase II study of a triple combination regimen …
Management of advanced pancreatic cancer with gemcitabine plus erlotinib: efficacy and safety results in clinical practice
RD Beveridge, V Alcolea, J Aparicio… - JOP. Journal of the …, 2014 - serena.unina.it
Context The combination of gemcitabine and erlotinib is a standard first-line treatment for
unresectable, locally advanced or metastatic pancreatic cancer. We reviewed our single …
unresectable, locally advanced or metastatic pancreatic cancer. We reviewed our single …
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada …
MJ Moore, D Goldstein, J Hamm, A Figer… - Journal of clinical …, 2007 - ascopubs.org
Purpose Patients with advanced pancreatic cancer have a poor prognosis and there have
been no improvements in survival since the introduction of gemcitabine in 1996. Pancreatic …
been no improvements in survival since the introduction of gemcitabine in 1996. Pancreatic …
Biweekly gemcitabine (GEM) in combination with erlotinib (ERL): an active and convenient regimen for advanced pancreatic cancer
A Ardavanis, P Kountourakis, A Karagiannis… - Anticancer …, 2009 - ar.iiarjournals.org
Background: Pancreatic cancer remains a disease of high mortality and one of the most
frustrating, resistant solid neoplasms to treat. The aim of this study was to evaluate a …
frustrating, resistant solid neoplasms to treat. The aim of this study was to evaluate a …
Gemcitabine (G) fixed-dose-rate infusion (FDR) plus erlotinib (E) in patients with advanced pancreatic cancer (APC).
A Munoz Llarena, J Mane, G Lopez-Vivanco… - Journal of Clinical …, 2011 - ascopubs.org
304 Background: G (30-minute infusion) plus E improves survival in patients with APC
compared with G alone. In a recent phase III trial, G-FDR showed a trend to better OS …
compared with G alone. In a recent phase III trial, G-FDR showed a trend to better OS …
A phase 1b study of erlotinib in combination with gemcitabine and nab-paclitaxel in patients with previously untreated advanced pancreatic cancer: an Academic …
SJ Cohen, BH O'Neil, J Berlin, P Ames… - Cancer chemotherapy …, 2016 - Springer
Purpose Addition of either nab-paclitaxel or erlotinib to gemcitabine to treat advanced
pancreatic cancer has demonstrated overall survival benefit. This study was conducted to …
pancreatic cancer has demonstrated overall survival benefit. This study was conducted to …
[HTML][HTML] First-line erlotinib and fixed dose-rate gemcitabine for advanced pancreatic cancer
V Vaccaro, E Bria, I Sperduti, A Gelibter… - World Journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To investigate activity, toxicity, and prognostic factors for survival of erlotinib and fixed
dose-rate gemcitabine (FDR-Gem) in advanced pancreatic cancer. METHODS: We …
dose-rate gemcitabine (FDR-Gem) in advanced pancreatic cancer. METHODS: We …
Gemcitabine plus erlotinib (GE) followed by capecitabine (C) versus capecitabine plus erlotinib (CE) followed by gemcitabine (G) in advanced pancreatic cancer (APC …
SH Boeck, U Vehling-Kaiser, D Waldschmidt… - Journal of Clinical …, 2010 - ascopubs.org
LBA4011 Background: Gemcitabine plus erlotinib (GE) is regarded as one standard of care
for patients (pts) with APC and CE as an all-oral regimen could be a feasible option in this …
for patients (pts) with APC and CE as an all-oral regimen could be a feasible option in this …
Dose finding and early efficacy study of gemcitabine plus capecitabine in combination with bevacizumab plus erlotinib in advanced pancreatic cancer
N Starling, D Watkins, D Cunningham… - Journal of clinical …, 2009 - ascopubs.org
Purpose This study evaluated safety and efficacy of chemotherapy (gemcitabine plus
capecitabine) plus bevacizumab/erlotinib in advanced pancreatic cancer because dual …
capecitabine) plus bevacizumab/erlotinib in advanced pancreatic cancer because dual …
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