Background Chronic airway infection contributes to the underlying pathogenesis of non-
cystic fibrosis bronchiectasis (NCFBr). In contrast to other chronic airway infections …

Rationale Despite the potentially important roles for infection in adult non-cystic fibrosis (CF)
bronchiectasis disease progression, the bacterial species present in the lower airways of …

A diverse microbiota exists within the airways of individuals with non-cystic fibrosis
bronchiectasis (nCFB). How the lung microbiome evolves over time, and whether changes …

Rationale: Characterization of bacterial populations in infectious respiratory diseases will
provide improved understanding of the relationship between the lung microbiota, disease …

Chronic bacterial infections play an important role in disease progression in patients with
bronchiectasis (BX) and cystic fibrosis (CF). Although only a few per cent of all bacteria can …

Background Molecular-based diagnostic techniques can compensate for the inherent
limitations of culture-based microbiology and provide a more comprehensive description of …

Chronic pulmonary sepsis is the predominant cause of morbidity for patients with cystic
fibrosis (CF) and non-CF bronchiectasis. Previously it was thought that respiratory infection …

Background. Recurrent bacterial infections play a key role in the pathogenesis of
bronchiectasis, but conventional microbiologic methods may fail to identify pathogens in …

Rationale: Although airway microbiota composition correlates with clinical measures in non–
cystic fibrosis bronchiectasis, these data are unlikely to provide useful prognostic information …

Non-cystic fibrosis bronchiectasis (NCFBr) is a major cause of morbidity due to frequent
infectious exacerbations. We analyzed the influence of patient age and bronchiectasis …