Low serotonin (5-hydroxytryptamine, 5-HT) neurotransmission is hypothesized in the
pathophysiology of suicide (for review see Bach and Arango, 2012; Mann, 2003; Träskman …

Suicide is a major public health concern and a leading cause of death in most societies.
Suicidal behaviour is complex and heterogeneous, likely resulting from several causes. It …

Several lines of evidence indicate that abnormalities in the functioning of the central
serotonergic system are involved in the pathogenesis of depressive illness and suicidal …

Abstract Reviews the book, The Neurobiology of Suicide: From the Bench to the Clinic. It is
described as the most recent and comprehensive book on the biology of suicide. The title …

Empirical study of suicide began early in this century from the sociological (Durkheim 1951)
and psychological (Freud 1956) perspective. A decade ago, a biological dimension was …

Suicide ranks among the leading causes of death around the world and takes a heavy
emotional and public health toll on most societies. Both distal and proximal factors contribute …

Abstract Purpose of Review The rising suicide rate in the USA will not be reversed without
improved risk assessment and prevention practices. To date, the best method for clinicians …

Over the last few years data have accumulated suggesting that there may be genetic and
biologic risk factors for suicide. This paper reviews studies from clinical populations, twins …

Predicting suicide is difficult due to the low base rate, even in high-risk groups, and the multi-
causal nature of suicidal behavior. Clinical predictors have shown low specificity …

Previous studies have shown that dysfunctions in the serotonin system and hypothalamic-
pituitary-adrenal axis (HPA) are associated strongly with suicidal behavior and suicide …