Neuroprotective and neurotrophic actions of glucagon‐like peptide‐1: an emerging opportunity to treat neurodegenerative and cerebrovascular disorders
I Salcedo, D Tweedie, Y Li… - British journal of …, 2012 - Wiley Online Library
Like type‐2 diabetes mellitus (T2DM), neurodegenerative disorders and stroke are an ever
increasing, health, social and economic burden for developed Westernized countries. Age is …
increasing, health, social and economic burden for developed Westernized countries. Age is …
Glucagon-like peptide-1: a focus on neurodegenerative diseases
M Grieco, A Giorgi, MC Gentile, M d'Erme… - Frontiers in …, 2019 - frontiersin.org
Diabetes mellitus is one of the major risk factors for cognitive dysfunction. The pathogenesis
of brain impairment caused by chronic hyperglycemia is complex and includes …
of brain impairment caused by chronic hyperglycemia is complex and includes …
GLP-1's role in neuroprotection: a systematic review
D Erbil, CY Eren, C Demirel, MU Küçüker, I Solaroğlu… - Brain injury, 2019 - Taylor & Francis
ABSTRACT Glucagon-like peptide 1 (GLP-1) is a target for treatment of diabetes; however,
its function in the brain is not well studied. In this systematic review, we aimed to analyze the …
its function in the brain is not well studied. In this systematic review, we aimed to analyze the …
The role of glia in the physiology and pharmacology of glucagon‐like peptide‐1: implications for obesity, diabetes, neurodegeneration and glaucoma
The medical applications of glucagon‐like peptide‐1 receptor (GLP‐1R) agonists is
evergrowing in scope, highlighting the urgent need for a comprehensive understanding of …
evergrowing in scope, highlighting the urgent need for a comprehensive understanding of …
Neuroprotective properties of GLP-1: theoretical and practical applications
JJ Holst, R Burcelin, E Nathanson - Current medical research and …, 2011 - Taylor & Francis
In the past few years, the development of pharmaceutical agents that enhance the
physiological effects of glucagon-like peptide-1 (GLP-1), either through GLP-1 receptor …
physiological effects of glucagon-like peptide-1 (GLP-1), either through GLP-1 receptor …
Glucagon-like peptide-1 and the central/peripheral nervous system: crosstalk in diabetes
G Muscogiuri, RA DeFronzo, A Gastaldelli… - Trends in Endocrinology …, 2017 - cell.com
Glucagon-like peptide-1 (GLP-1) is released in response to meals and exerts important roles
in the maintenance of normal glucose homeostasis. GLP-1 is also important in the regulation …
in the maintenance of normal glucose homeostasis. GLP-1 is also important in the regulation …
Alternative role of glucagon-like Peptide-1 receptor agonists in neurodegenerative diseases
Aging is a crucial risk factor for common neurodegenerative diseases, such as Alzheimer's
disease (AD) and Parkinson's disease (PD). Limited options are available for the treatment …
disease (AD) and Parkinson's disease (PD). Limited options are available for the treatment …
Glucagon‐like peptide‐1 (GLP‐1) signalling in the brain: From neural circuits and metabolism to therapeutics
A Kabahizi, B Wallace, L Lieu, D Chau… - British Journal of …, 2022 - Wiley Online Library
Glucagon‐like‐peptide‐1 (GLP‐1) derived from gut enteroendocrine cells and a discrete
population of neurons in the caudal medulla acts through humoral and neural pathways to …
population of neurons in the caudal medulla acts through humoral and neural pathways to …
[HTML][HTML] Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration
According to World Health Organization estimates, type 2 diabetes (T2D) is an epidemic
(particularly in under development countries) and a socio-economic challenge. This is even …
(particularly in under development countries) and a socio-economic challenge. This is even …
[HTML][HTML] Recent advances in understanding the role of glucagon-like peptide 1
J Reed, SC Bain, V Kanamarlapudi - F1000Research, 2020 - ncbi.nlm.nih.gov
The discovery that glucagon-like peptide 1 (GLP-1) mediates a significant proportion of the
incretin effect during the postprandial period and the subsequent observation that GLP-1 …
incretin effect during the postprandial period and the subsequent observation that GLP-1 …