Aim: This study is designed to investigate the superiority and applicability of the model
among the linear-quadratic (LQ), linear-quadratic-linear (LQ-L) and universal-survival-curve …

Objective: The applicability of the linear quadratic (LQ) model to local control (LC) modeling
after hypofractionated radiotherapy to treat lung cancer is highly debated. To date, the …

Purpose To examine the equivalent uniform dose (EUD) formalism using the universal
survival curve (USC) applicable to high-dose stereotactic body radiotherapy (SBRT) …

Background and purpose To compare the linear-quadratic (LQ) and the LQ-L formalism
(linear cell survival curve beyond a threshold dose d T) for modeling local tumor control …

We proposed a new mathematical model that combines an ordinary differential equation
(ODE) and microdosimetric kinetic model (MKM) to predict the tumor-cell lethal effect of …

PURPOSE: Overprediction of the potency and toxicity of high-dose ablative radiotherapy
such as stereotactic body radiotherapy (SBRT) by the linear quadratic (LQ) model led to …

Purpose The study aims to develop and validate a combined model for predicting 3-year
cancer-specific survival (CSS) in lung cancer patients treated with stereotactic body …

Purpose: To estimate the risk of radiation-induced changes in the lung before single-dose
treatment (stereotactic body radiation therapy [SBRT]) of lung cancer, the quantitative dose …

This work is to analyze pooled clinical data using different radiobiological models and to
understand the relationship between biologically effective dose (BED) and tumor control …

We hypothesize that the correlation between the radiation dose expressed as the
biologically effective dose (BED) and the clinical endpoints will correlate better as the value …