Transforming growth factor-β (TGF-β)-mediated epithelial mesenchymal transition (EMT) of
human lung cancer cells may contribute to lung cancer metastasis. It has been reported that …

Background Chronic persistent asthma is characterized by ongoing airway inflammation and
airway remodeling. The processes leading to airway remodeling are poorly understood, and …

Transforming growth factor (TGF)-β is an evolutionarily conserved pleiotropic factor that
regulates a myriad of biological processes including development, tissue regeneration …

Breast cancer progression toward metastatic disease is linked to re-activation of epithelial–
mesenchymal transition (EMT), a latent developmental process. Breast cancer cells …

Epithelial to mesenchymal transition (EMT) is a process that allows an epithelial cell to
acquire a mesenchymal phenotype through multiple biochemical changes resulting in an …

Abstract Epithelial-mesenchymal transition (EMT), a key step in the early stages of cancer
metastasis, is orchestrated by several signaling pathways, including IL-6/JAK/STAT3 and …

Background Lung cancer is one of the most prevalent neoplasias in developed countries.
Advances in patient survival have been limited and the identification of prognostic molecules …

Transforming growth factor beta (TGF-β) induces epithelial–mesenchymal transition (EMT)
accompanied by cellular differentiation and migration. Despite extensive transcriptomic …

Recently, epithelial-mesenchymal transition (EMT) has been reported to contribute to tissue
fibrosis through enhanced transforming growth factor (TGF)-β1 signaling. Tumor necrosis …

The differentiation plasticity of epithelial cells that mediates TGF-β-induced EMT and
reversion from mesenchymal to epithelial phenotype are increasingly seen as integral …