Distinguished effects of antiphospholipid antibodies and anti-oxidized LDL antibodies on oxidized LDL uptake by macrophages
K Kobayashi, K Tada, H Itabe, T Ueno, PH Liu… - Lupus, 2007 - journals.sagepub.com
Several interpretations have been made regarding the specificity of antiphospholipid
antibodies and antibodies against oxidized low-density lipoprotein (oxLDL), but these are …
antibodies and antibodies against oxidized low-density lipoprotein (oxLDL), but these are …
Atherogenic antiphospholipid antibodies in antiphospholipid syndrome
K Kobayashi, LR Lopez… - Annals of the New York …, 2007 - Wiley Online Library
Macrophage uptake of oxidized LDL (oxLDL) plays a critical role in early stages of
atherosclerosis. We previously reported that oxLDL forms stable complexes with β2 …
atherosclerosis. We previously reported that oxLDL forms stable complexes with β2 …
Oxidized LDL/β2-glycoprotein I complexes: new aspects in atherosclerosis
E Matsuura, K Kobayashi, K Inoue, LR Lopez… - Lupus, 2005 - journals.sagepub.com
β2-glycoprotein I (β2GPI) is a major antigenic target for antiphospholipid antibodies.
Oxidized low-density lipoprotein (oxLDL) is the principal lipoprotein found in atherosclerotic …
Oxidized low-density lipoprotein (oxLDL) is the principal lipoprotein found in atherosclerotic …
OxLDL/β2GPI complexes and autoantibodies in patients with systemic lupus erythematosus, systemic sclerosis, and antiphospholipid syndrome: pathogenic …
LR Lopez, DF Simpson, BL Hurley… - Annals of the New …, 2005 - Wiley Online Library
Oxidized low‐density lipoprotein (oxLDL) interacts with β2GPI, forming oxLDL/β2GPI
complexes. Autoimmune vascular inflammation (and oxidative stress) may promote the …
complexes. Autoimmune vascular inflammation (and oxidative stress) may promote the …
[HTML][HTML] Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid–protein adducts inhibit macrophage uptake of oxidized low-density …
S Hörkkö, DA Bird, E Miller, H Itabe… - The Journal of …, 1999 - Am Soc Clin Investig
We recently cloned monoclonal IgM autoantibodies which bind to epitopes of oxidized low-
density lipoprotein (OxLDL) from apoE-deficient mice (EO–autoantibodies). We now …
density lipoprotein (OxLDL) from apoE-deficient mice (EO–autoantibodies). We now …
Are oxidized LDL/β2‐glycoprotein I complexes pathogenic antigens in autoimmune‐mediated atherosclerosis?
E Matsuura, LR Lopez - Journal of Immunology Research, 2004 - Wiley Online Library
The oxidative modification of low‐density lipoprotein (LDL) in the intima of arteries
contributes to the initiation and progression of atherosclerotic lesions. We have previously …
contributes to the initiation and progression of atherosclerotic lesions. We have previously …
Immunogenic oxidized low-density lipoprotein/β2-glycoprotein I complexes in the diagnostic management of atherosclerosis
LR Lopez, K Kobayashi, Y Matsunami… - Clinical reviews in allergy …, 2009 - Springer
Oxidized low-density lipoprotein (oxLDL) promotes atherosclerosis through a complex
interaction of inflammatory and immunologic factors that lead to macrophage lipid uptake …
interaction of inflammatory and immunologic factors that lead to macrophage lipid uptake …
The role of innate and adaptive immunity to oxidized low‐density lipoprotein in the development of atherosclerosis
K Kobayashi, LR Lopez, Y Shoenfeld… - Annals of the New …, 2005 - Wiley Online Library
Atherosclerosis is a chronic inflammatory process of the arterial wall associated with
systemic and local immune responses to various antigens, oxidized low‐density lipoprotein …
systemic and local immune responses to various antigens, oxidized low‐density lipoprotein …
Antiphospholipid antibodies and atherosclerosis
E Matsuura, K Kobayashi, T Yasuda, T Koike - Lupus, 1998 - journals.sagepub.com
β2-Glycoprotein I (β2-GPI) is a major antigen for anticardiolipin antibodies (aCL) induced in
patients with antiphospholipid syndrome and their antigenic epitopes are cryptic. The …
patients with antiphospholipid syndrome and their antigenic epitopes are cryptic. The …
Atherogenic oxidized low-density lipoprotein/β2-glycoprotein I (oxLDL/β2GPI) complexes in patients with systemic lupus erythematosus and antiphospholipid …
E Matsuura, K Kobayashi, BL Hurley, LR Lopez - Lupus, 2006 - journals.sagepub.com
Oxidized low-density lipoprotein (oxLDL) interacts in vitro with β 2-glycoprotein I (β 2GPI) via
LDL-derived specific ligands forming oxLDL/β 2GPI complexes. Circulating oxLDL/β 2GPI …
LDL-derived specific ligands forming oxLDL/β 2GPI complexes. Circulating oxLDL/β 2GPI …
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