[HTML][HTML] The neurobiological mechanism underlying hypothalamic GnRH pulse generation: the role of kisspeptin neurons in the arcuate nucleus
TM Plant - F1000Research, 2019 - ncbi.nlm.nih.gov
This review recounts the origins and development of the concept of the hypothalamic
gonadotropin-releasing hormone (GnRH) pulse generator. It starts in the late 1960s when …
gonadotropin-releasing hormone (GnRH) pulse generator. It starts in the late 1960s when …
Neuroendocrine control of gonadotropin‐releasing hormone: pulsatile and surge modes of secretion
RL Goodman, AE Herbison… - Journal of …, 2022 - Wiley Online Library
The concept that different systems control episodic and surge secretion of gonadotropin‐
releasing hormone (GnRH) was well established by the time that GnRH was identified and …
releasing hormone (GnRH) was well established by the time that GnRH was identified and …
New insights into the control of pulsatile GnRH release: the role of Kiss1/neurokinin B neurons
VM Navarro - Frontiers in endocrinology, 2012 - frontiersin.org
Gonadotropin-releasing hormone (GnRH) is the ultimate output signal of an intricate network
of neuroendocrine factors that, acting on the pituitary, trigger gonadotropin release. In turn …
of neuroendocrine factors that, acting on the pituitary, trigger gonadotropin release. In turn …
Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus
K Maeda, S Ohkura, Y Uenoyama, Y Wakabayashi… - Brain research, 2010 - Elsevier
Gonadotropin-releasing hormone (GnRH) secretion has two modes of release in
mammalian species; the surge mode and the pulse mode. The surge mode, which is …
mammalian species; the surge mode and the pulse mode. The surge mode, which is …
Hypothalamic kisspeptin neurons as potential mediators of estradiol negative and positive feedback
JR Starrett, SM Moenter - Peptides, 2023 - Elsevier
Gonadal steroid feedback regulates the brain's patterned secretion of gonadotropin-
releasing hormone (GnRH). Negative feedback, which occurs in males and during the …
releasing hormone (GnRH). Negative feedback, which occurs in males and during the …
[HTML][HTML] Mechanism of pulsatile GnRH release in primates: Unresolved questions
E Terasawa - Molecular and cellular endocrinology, 2019 - Elsevier
The pulsatility of GnRH release is essential for reproductive function. The key events in
reproductive function, such as puberty onset and ovulatory cycles, are regulated by the …
reproductive function, such as puberty onset and ovulatory cycles, are regulated by the …
Does the KNDy model for the control of gonadotropin-releasing hormone pulses apply to monkeys and humans?
There is now considerable evidence supporting the role of a subpopulation of neurons in the
arcuate nucleus of the hypothalamus that coexpress kisspeptin, neurokinin B, and dynorphin …
arcuate nucleus of the hypothalamus that coexpress kisspeptin, neurokinin B, and dynorphin …
Role of kisspeptin neurons as a GnRH surge generator: Comparative aspects in rodents and non‐rodent mammals
F Matsuda, S Ohkura, F Magata… - Journal of Obstetrics …, 2019 - Wiley Online Library
Ovulation is an essential phenomenon for reproduction in mammalian females along with
follicular growth. It is well established that gonadal function is controlled by the …
follicular growth. It is well established that gonadal function is controlled by the …
[HTML][HTML] Physiology of GNRH and gonadotropin secretion
P Marques, K Skorupskaite, KS Rozario… - Endotext …, 2022 - ncbi.nlm.nih.gov
Gonadotropin hormone-releasing hormone (GnRH) is the key regulator of the reproductive
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …
Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretion
Recently, a subset of neurons was identified in the arcuate nucleus of the hypothalamus that
colocalize three neuropeptides, kisspeptin, neurokinin B, and dynorphin, each of which has …
colocalize three neuropeptides, kisspeptin, neurokinin B, and dynorphin, each of which has …