Anticancer activity of oleiferoside B involving autophagy and apoptosis through increasing ROS release in MCF-7 cells and SMMC-7721 cells

S Feng, Z Zha, Z Wang, P Yang, J Wu, X Li… - Natural Product …, 2021 - Taylor & Francis
Oleiferoside B is a triterpenoid monomer compound, mainly isolated from roots of Camellia
oleifera Abel, the underlying mechanism of its antitumour is not clear. In the present study …

Oleiferoside W from the roots of Camellia oleifera C. Abel, inducing cell cycle arrest and apoptosis in A549 cells

JP Wu, NX Kang, MY Zhang, HW Gao… - Journal of Asian …, 2018 - Taylor & Francis
Camellia oleifera C. Abel has been widely cultivated in China, and a group of bioactive
constituents such as triterpeniod saponin have been isolated from C. oleifera C. Abel. In the …

[HTML][HTML] Eupalinolide O, a novel sesquiterpene lactone from Eupatorium lindleyanum DC., induces cell cycle arrest and apoptosis in human MDA-MB-468 breast …

B Yang, Y Zhao, C Lou, H Zhao - Oncology Reports, 2016 - spandidos-publications.com
Sesquiterpene lactones have been confirmed to have potential antitumor activity. Here, we
demonstrated that Eupalinolide O (EO), a novel sesquiterpene lactone isolated from …

Eupalinolide A induces autophagy via the ROS/ERK signaling pathway in hepatocellular carcinoma cells in vitro and in vivo

Y Zhang, F Dong, Z Cao, T Wang… - International …, 2022 - spandidos-publications.com
Hepatocellular carcinoma is the most common primary malignancy of the liver. The current
systemic drugs used to treat hepatocellular carcinoma result in low overall survival time. It …

Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro

B Sun, L Gao, A Ahsan, P Chu, Y Song, H Li… - International …, 2016 - Elsevier
Oleanolic acid (OA) and its several derivatives possess various pharmacological activities,
such as antitumor and anti-inflammation. In present study, anticancer effect of SZC015, an …

Oleifolioside B-mediated autophagy promotes apoptosis in A549 human non-small cell lung cancer cells

CY Jin, HY Yu, C Park, MH Han… - International …, 2013 - spandidos-publications.com
The biochemical mechanisms of cell death by oleifolioside B (OB), a cycloartane-type
triterpene glycoside isolated from Dendropanax morbifera Leveille, were investigated in …

Cytotoxic constituents from Celastrus paniculatus induce apoptosis and autophagy in breast cancer cells

JR Weng, MH Yen, WY Lin - Phytochemistry, 2013 - Elsevier
Celastrus paniculatus is a traditional medicinal plant with diverse pharmacological activities.
To identify its bioactive constituents, three new β-dihydroagarofuranoid sesquiterpenes were …

EM-2, a natural sesquiterpene lactone from Elephantopus mollis HBK, enhanced the sensitivity of breast cancer cells to epirubicin by blocking protective autophagy

J Li, J Zhou, N Zhao, Z Li, X Xu, J Tang, Z Li, X Zhang… - Phytomedicine, 2023 - Elsevier
Background EM-2, a natural sesquiterpene lactone isolated from Elephantopus mollis HBK,
showed a good anti-breast cancer effect when combined with epirubicin (EPI). However, its …

NF-κB activation was involved in reactive oxygen species-mediated apoptosis and autophagy in 1-oxoeudesm-11 (13)-eno-12, 8α-lactone-treated human lung cancer …

S Liu, D Wu, L Li, X Sun, W Xie, X Li - Archives of pharmacal research, 2014 - Springer
oxoeudesm-11 (13)-eno-12, 8α-lactone (OEL), a novel eudesmane-type sesquiterpene
compound, has been shown to inhibit the growth of some cancer cell lines and induce …

Mechanism study of oleanolic acid derivative, K73-03, inducing cell apoptosis in hepatocellular carcinoma

J Wang, C Ma, Z Tang, Z Sun, E Qaed, X Chi… - Cancer Cell …, 2024 - Springer
Abstract Oleanolic acid (3β-hydroxyolean-12-en-28-oic acid, OA) is a kind of pentacyclic
triterpene, which widely distributes in nature. OA possesses a powerful anti-cancer effect; …