mRNA Destabilizing Factors: Tristetraprolin Expression at the Porcine Maternal–Fetal Interface
Problem To evaluate the expression of the tristetraprolin family and their selected targets
during porcine pregnancy. Method of study Using qPCR and Western blot, mRNA and …
during porcine pregnancy. Method of study Using qPCR and Western blot, mRNA and …
[HTML][HTML] RNA binding protein, tristetraprolin in a murine model of recurrent pregnancy loss
K Khalaj, RL Luna, MER de França, WH de Oliveira… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Recurrent pregnancy loss is a major reproductive pathology affecting 1-5% of pregnant
women worldwide. A distinct feature of this reproductive pathology is involvement of key …
women worldwide. A distinct feature of this reproductive pathology is involvement of key …
[PDF][PDF] RETRACTED: elevated tristetraprolin impairs trophoblast invasion in women with recurrent miscarriage by destabilization of HOTAIR
FJ Tian, XY He, J Wang, X Li, XL Ma, F Wu… - … Therapy-Nucleic Acids, 2018 - cell.com
Tristetraprolin (TTP) regulates the stability of multiple targets that have important biological
roles. However, the role of TTP in trophoblasts at the maternal-fetal interface remains poorly …
roles. However, the role of TTP in trophoblasts at the maternal-fetal interface remains poorly …
[HTML][HTML] Expression of the mRNA stability regulator Tristetraprolin is required for lactation maintenance in the mouse mammary gland
MV Goddio, A Gattelli, JM Tocci, LP Cuervo, M Stedile… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Abstract Tristetraprolin (TTP), an mRNA-binding protein that negatively controls levels of
inflammatory factors, is highly expressed in the lactating mouse mammary gland. To …
inflammatory factors, is highly expressed in the lactating mouse mammary gland. To …
Tristetraprolin promotes survival of mammary progenitor cells by restraining TNFα levels
M Stedile, A Lara Montero, ME García Solá… - Frontiers in Cell and …, 2024 - frontiersin.org
Tristetraprolin (TTP) is an RNA binding protein that destabilizes mRNAs of factors involved
in proliferation, invasiveness, and inflammation. Disruption of the gene that codes for TTP …
in proliferation, invasiveness, and inflammation. Disruption of the gene that codes for TTP …
Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin …
DJ Stumpo, NA Byrd, RS Phillips, S Ghosh… - … and cellular biology, 2004 - Am Soc Microbiol
The mouse gene Zfp36L1 encodes zinc finger protein 36-like 1 (Zfp36L1), a member of the
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …
Zfp36l3, a Rodent X Chromosome Gene Encoding a Placenta-Specific Member of the Tristetraprolin Family of CCCH Tandem Zinc Finger Proteins
PJ Blackshear, RS Phillips, S Ghosh… - Biology of …, 2005 - academic.oup.com
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger (TZF) proteins can
bind directly to AU-rich elements (ARE) in mRNA, causing deadenylation and destabilization …
bind directly to AU-rich elements (ARE) in mRNA, causing deadenylation and destabilization …
A unique C-terminal repeat domain maintains the cytosolic localization of the placenta-specific tristetraprolin family member ZFP36L3
ED Frederick, SBV Ramos, PJ Blackshear - Journal of Biological Chemistry, 2008 - ASBMB
Members of the tristetraprolin family of CCCH tandem zinc finger proteins bind to AU-rich
elements in certain cellular mRNAs, leading to their deadenylation and destabilization …
elements in certain cellular mRNAs, leading to their deadenylation and destabilization …
Deficiency of the placenta-and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron …
DJ Stumpo, CS Trempus, CJ Tucker, W Huang… - …, 2016 - journals.biologists.com
The ZFP36L3 protein is a rodent-specific, placenta-and yolk sac-specific member of the
tristetraprolin (TTP) family of CCCH tandem zinc finger proteins. These proteins bind to AU …
tristetraprolin (TTP) family of CCCH tandem zinc finger proteins. These proteins bind to AU …
[HTML][HTML] Dominant suppression of inflammation via targeted mutation of the mRNA destabilizing protein tristetraprolin
EA Ross, T Smallie, Q Ding, JD O'Neil… - The Journal of …, 2015 - journals.aai.org
In myeloid cells, the mRNA-destabilizing protein tristetraprolin (TTP) is induced and
extensively phosphorylated in response to LPS. To investigate the role of two specific …
extensively phosphorylated in response to LPS. To investigate the role of two specific …