Abstract Background Amyotrophic Lateral Sclerosis (ALS) is a lethal disorder characterized
by progressive degeneration of motor neurons in the brain and spinal cord. Diagnosis is …

Amyotrophic lateral sclerosis (ALS) is a terminal late-onset condition characterized by the
loss of upper and lower motor neurons. Mutations in more than 30 genes are associated to …

The description of group-level, genotype-and phenotype-associated imaging traits is
academically important, but the practical demands of clinical neurology centre on the …

Amyotrophic lateral sclerosis (ALS) is an untreatable and fatal neurodegenerative disease
that is identified by the loss of motor neurons in the spinal cord, brain stem, and motor cortex …

Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative disease,
and only modest disease-modifying strategies have been established to date. Numerous …

Objective To determine the diagnostic and prognostic significance of neurofilament light
chain (NfL), TAR DNA‐binding protein 43 (TDP‐43), and total tau (t‐tau) in cerebrospinal …

Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …

Neurophysiological biomarkers in amyotrophic lateral scleros... : Current Opinion in
Neurology Neurophysiological biomarkers in amyotrophic lateral sclerosis : Current Opinion …

Amyotrophic lateral sclerosis (ALS), the commonest adult-onset motor neuron disorder, is
characterized by a survival span of only 2–5 years after onset. Relevant biomarkers or …

Abstract Purpose of Review: This article reviews the clinical features, diagnostic pathway,
therapies, and current understanding of the pathophysiology of amyotrophic lateral sclerosis …