To determine whether epithelial ion transport is physiologically important for lung water
clearance after birth, the sodium transport inhibitor amiloride or its vehicle saline was given …

Materials and Methods Newborn Lung Water Clearance To evaluate the effect of
pharmacologic agents on the clearance of lung liquid from newborn guinea pigs, we used …

Transition from placental to pulmonary oxygenation at birth depends on a rapid removal of
fetal lung fluid from the developing alveoli. Alveolar fluid clearance was examined in …

Background: Recent phase-contrast X-ray imaging studies suggest that inspiration primarily
drives lung aeration and airway liquid clearance at birth, which questions the role of …

The ability of the distal lung epithelia to actively transport Na+, with Cl− and water following,
from the alveolar spaces inversely correlates with morbidity and mortality of infants, children …

Adrenaline was infused intravenously at rates of 0.1‐1.0 microgram/min into chronically
catheterized fetal lambs (125‐141 days gestation) to induce slowing of secretion or …

This article reviews the process of alveolar fluid clearance at birth and its relevance to
successful transition from placental to pulmonary gas exchange. Although mechanical …

Regulation of active Na+ transport across fetal distal lung epithelial cells (FDLE) by
corticosterone (CST), corticotropin-releasing hormone (CRH), and oxygen tension may be …

Pulmonary oedema results from an imbalance between the forces driving fluid into the
airspace and the biological mechanisms for its removal. In mice lacking the α‐subunit of the …

We have developed a simple isolated lung preparation for measurement of liquid and solute
fluxes across mouse alveolar epithelium. Liquid instilled into air spaces was absorbed at the …