Abstract Transcription factor Nrf2 (NF-E2-related factor 2) is essential for oxidative and
electrophilic stress responses. While it has been well characterized that Nrf2 activity is tightly …

Regulation of antioxidant gene expression is essential for controlling oxidative stress and
maintaining physiological homeostasis. In this context, the nuclear factor E2-related factor 2 …

Several years have passed since NF-E2-related factor 2 (Nrf2) was demonstrated to
regulate the induction of genes encoding antioxidant proteins and phase 2 detoxifying …

Importance of the field: Oxidative stress has been implicated in the pathogenesis of
pulmonary emphysema. Nuclear factor erythroid-2-related factor 2 (Nrf2) a major antioxidant …

Several convergent destructive mechanisms such as oxidative stress, alveolar cell
apoptosis, extracellular matrix proteolysis and chronic inflammation contribute to chronic …

Environmental risk factors, including noise, air pollution, chemical agents, ultraviolet
radiation (UVR) and mental stress have a considerable impact on human health. Oxidative …

Nuclear factor, erythroid‐derived 2, like 2 (NRF2) is a key regulator of antioxidants and
cellular stress responses. The role of NRF2 in pulmonary neoplasia, a diverse disease for …

The gene expression program induced by NRF2 transcription factor plays a critical role in
cell defense responses against a broad variety of cellular stresses, most importantly …

Inflammation is a key driver in many pathological conditions such as allergy, cancer,
Alzheimer's disease, and many others, and the current state of available drugs prompted …

The NF-E2-related factor 2 (Nrf2)-mediated signalling pathway provides living organisms an
efficient and pivotal line of defensive to counteract environmental insults and endogenous …