Human microbiome as an approach to personalized medicine

S Hasani-Ranjbar, B Larijani - Alternative therapies in health …, 2017 - search.proquest.com
Personalized medicine is an approach for medical decisions, practices, and interventions
that considers individual variations in genes, environment, and lifestyle for each person …

Characterization of fungal and bacterial components in gut/fecal microbiome

R Kirschner, T Hsu, N Ngoc Tuan… - Current Drug …, 2015 - ingentaconnect.com
The gut microbiota is a complex ecosystem that affects the development, nutritional status
and immunological responses of the host. Prokaryotes and fungi in the community have the …

[HTML][HTML] Metabolic phenotypes as potential biomarkers for linking gut microbiome with inflammatory bowel diseases

SN Iablokov, NS Klimenko, DA Efimova… - Frontiers in Molecular …, 2021 - frontiersin.org
The gut microbiome is of utmost importance to human health. While a healthy microbiome
can be represented by a variety of structures, its functional capacity appears to be more …

The human microbiome

HE Blum - Advances in medical sciences, 2017 - Elsevier
Until recently, human microbiology was based on the identification of single microbes, such
as bacteria, fungi and viruses, frequently isolated from patients with acute or chronic …

Exploiting gut microbial traits and trade-offs in microbiome-based therapeutics

B Liu, DR Garza, P Saha, X Zhou, K Faust - Nature Reviews …, 2024 - nature.com
The clinical translation of therapeutics on the basis of human gut microorganisms is
hampered by our limited knowledge of how microbes survive and adapt to fluctuating …

[HTML][HTML] Key technologies for progressing discovery of microbiome-based medicines

RB Young, VR Marcelino, M Chonwerawong… - Frontiers in …, 2021 - frontiersin.org
A growing number of experimental and computational approaches are illuminating the
“microbial dark matter” and uncovering the integral role of commensal microbes in human …

Evaluating the latest high-throughput molecular techniques for the exploration of microbial gut communities

MJ Claesson, PW O'Toole - Gut Microbes, 2010 - Taylor & Francis
The human gut microbiota has become the subject of an increasing amount of attention, due
to an emerging understanding of its role in maintaining health throughout our lives. Since …

Microbiome 101: studying, analyzing, and interpreting gut microbiome data for clinicians

C Allaband, D McDonald, Y Vázquez-Baeza… - Clinical …, 2019 - Elsevier
Advances in technical capabilities for reading complex human microbiomes are leading to
an explosion of microbiome research, leading in turn to intense interest among clinicians in …

Big data and tiny proteins: shining a light on the dark corners of the gut microbiome

S Devkota - Nature Reviews Gastroenterology & Hepatology, 2020 - nature.com
In 2019, there have been substantial advances in our understanding of the gut microbiome.
Key developments include an improved gut-on-a-chip system, a search for small proteins …

Culturomics: a new kid on the block of OMICS to enable personalized medicine

ME Kambouris, C Pavlidis, E Skoufas… - Omics: a journal of …, 2018 - liebertpub.com
This innovation analysis highlights the underestimated and versatile potential of the new
field of culturomics and examines its relation to other OMICS system sciences such as …