Objective To determine to what extent prostate cancer (PCa) risk prediction is improved by
adding prostate-specific antigen (PSA) to a baseline model including genetic risk. Methods …

Purpose Single-nucleotide polymorphism (SNP) panel tests have been proposed for use in
the detection of, and prediction of risk for, prostate cancer and as prognostic indicator in …

Simple Summary Prostate cancer is a common disease in older men, yet current risk
prediction models for prostate cancer do not discriminate between men at higher risk of …

BACKGROUND Genome‐wide association studies (GWAS) have identified more than 30
single nucleotide polymorphisms (SNPs) that were reproducibly associated with prostate …

Prostate cancer (PCa) is the most common cancer among men with a lifetime risk of 12%
and median age of diagnosis of 66. 1 In 2020, 191,930 new cases are expected to be …

Background Single nucleotide polymorphism–based genetic risk score (GRS) has been
developed and validated for prostate cancer (PCa) risk assessment. As GRS is population …

The modern research on molecular basis of prostate cancer (PCa) development includes
studies aiming to identify potential genetic markers which could be used in diagnostics …

Objectives: The aim of the study is to review biotechnology advances in gene expression
profiling on prostate cancer (PCa), focusing on experimental platform development and …

Polygenic risk scores (PRS) for prostate cancer incidence have been proposed to optimize
prostate cancer screening. Prediction of lethal prostate cancer is key to any stratified …

Prostate cancer (PC) is the most common malignancy observed in men. It is evident that
genetic factors play some important roles in PC etiology. Recently, genome‐wide …