High-quality identification of volatile organic compounds (VOCs) originating from breath

W Arulvasan, H Chou, J Greenwood, ML Ball, O Birch… - Metabolomics, 2024 - Springer
Abstract Introduction Volatile organic compounds (VOCs) can arise from underlying
metabolism and are detectable in exhaled breath, therefore offer a promising route to non …

Progress and challenges of developing volatile metabolites from exhaled breath as a biomarker platform

H Chou, L Godbeer, M Allsworth, B Boyle, ML Ball - Metabolomics, 2024 - Springer
Background The multitude of metabolites generated by physiological processes in the body
can serve as valuable biomarkers for many clinical purposes. They can provide a window …

Analysis of biogenic volatile organic compounds in human health and disease

J Dummer, M Storer, M Swanney, M McEwan… - TrAC Trends in …, 2011 - Elsevier
The analysis of volatile biomarkers of disease in breath is attractive because breath analysis
is non-invasive and quick, and allows for repeated sampling. Challenges faced in the …

Volatile compounds in human breath: critical review and meta-analysis

T Issitt, L Wiggins, M Veysey, ST Sweeney… - Journal of Breath …, 2022 - iopscience.iop.org
Volatile compounds contained in human breath reflect the inner workings of the body. A
large number of studies have been published that link individual components of breath to …

[PDF][PDF] Challenges in the investigation of volatile disease biomarkers in urine

J Kwak, G Preti - Volatile Biomarkers, 2013 - academia.edu
Distinctive odors or volatile profiles are often a consequence of disease. A portion of these
volatile organic compounds (VOCs) are excreted into the exhaled breath and urine and …

[HTML][HTML] Diagnostic potential of breath analysis–focus on the dynamics of volatile organic compounds

W Miekisch, P Sukul, JK Schubert - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Abstract Analysis of exhaled volatile organic compounds (VOCs) holds promise for the
development of new and non-invasive procedures in many areas of clinical and home care …

Breathomics in lung disease

MP Van Der Schee, T Paff, P Brinkman… - Chest, 2015 - Elsevier
Volatile organic compounds (VOCs) are produced by virtually all metabolic processes of the
body. As such, they have potential to serve as noninvasive metabolic biomarkers. Since …

Taking your breath away: metabolomics breathes life in to personalized medicine

NJW Rattray, Z Hamrang, DK Trivedi, R Goodacre… - Trends in …, 2014 - cell.com
Breath-based metabolomics (breathomics) is an exciting developing area of biotechnology
that centers on the capture, identification, and quantification of volatile organic compound …

Methodology validation, intra-subject reproducibility and stability of exhaled volatile organic compounds

M Basanta, B Ibrahim, D Douce, M Morris… - Journal of Breath …, 2012 - iopscience.iop.org
Robust methods for breath sampling and analysis are required for potential clinical
applications. We have evaluated an improved sampling and experimental design, assessing …

[HTML][HTML] Breath biomarkers in Non-Carcinogenic diseases

PC Moura, M Raposo, V Vassilenko - Clinica Chimica Acta, 2023 - Elsevier
The analysis of volatile organic compounds (VOCs) from human matrices like breath,
perspiration, and urine has received increasing attention from academic and medical …