[HTML][HTML] Gene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targets

G Capurso, S Lattimore… - Endocrine-related …, 2006 - erc.bioscientifica.com
The intrinsic nature of tumour behaviour (stable vs progressive) and the presence of liver
metastases are key factors in determining the outcome of patients with a pancreatic …

Identification of potential therapeutic targets by gene-expression profiling in pancreatic endocrine tumors

A Couvelard, J Hu, G Steers, OT Dermot, A Sauvanet… - Gastroenterology, 2006 - Elsevier
Background & Aims: Prediction of biological behavior in pancreatic endocrine tumors (PET)
is difficult on histologic criteria alone. The aim of this study was to characterize PET gene …

Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays

A Maitra, DE Hansel, P Argani, R Ashfaq… - Clinical Cancer …, 2003 - AACR
Abstract Purpose: Pancreatic endocrine neoplasms (PENs) are rare, mostly well-
differentiated endocrine neoplasms, whose biology has been poorly characterized. Global …

Molecular profile of pancreatic neuroendocrine neoplasms (PanNENs): Opportunities for personalized therapies

J Arakelyan, D Zohrabyan, PA Philip - Cancer, 2021 - Wiley Online Library
Pancreatic neuroendocrine neoplasms (panNENs) are the second most common epithelial
tumors of the pancreas. Despite improvements in prognostic grading and staging systems, it …

[HTML][HTML] Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway

E Missiaglia, I Dalai, S Barbi, S Beghelli… - Journal of clinical …, 2010 - ncbi.nlm.nih.gov
Pancreatic Endocrine Tumors: Expression Profiling Evidences a Role for AKT-mTOR Pathway
- PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Gene expression signatures identify novel therapeutics for metastatic pancreatic neuroendocrine tumors

AT Scott, M Weitz, PJ Breheny, PH Ear, B Darbro… - Clinical cancer …, 2020 - AACR
Purpose: Pancreatic neuroendocrine tumors (pNETs) are uncommon malignancies noted for
their propensity to metastasize and comparatively favorable prognosis. Although both the …

Molecular pathology and genetics of pancreatic endocrine tumours.

G Capurso, S Festa, R Valente, M Piciucchi… - Journal of molecular …, 2012 - europepmc.org
Pancreatic neuroendocrine tumours (PETs) are the second most frequent pancreatic
neoplasms. Their poor chemosensitivity, high rate of metastatic disease and relatively long …

Genomic imbalances in the progression of endocrine pancreatic tumors

J Zhao, H Moch, AF Scheidweiler… - Genes …, 2001 - Wiley Online Library
Endocrine pancreatic tumors (EPTs) are neoplasms with malignant potential. To explore the
molecular basis of metastatic progression in human EPTs, we analyzed 17 paired …

A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic …

A Sadanandam, S Wullschleger, CA Lyssiotis… - Cancer discovery, 2015 - AACR
Seeking to assess the representative and instructive value of an engineered mouse model
of pancreatic neuroendocrine tumors (PanNET) for its cognate human cancer, we profiled …

Identification of molecular markers specific for pancreatic neuroendocrine tumors by genetic profiling of core biopsies

M Bloomston, A Durkin, I Yang, M Rojiani… - Annals of surgical …, 2004 - Springer
Background: There is a paucity of known molecular markers that distinguish pancreatic
neuroendocrine tumors from other pancreatic tumor types. We hypothesized that novel …