Gene expression profiling in lymph node-positive and lymph node-negative pancreatic cancer

HN Kim, DW Choi, KT Lee, JK Lee, JS Heo, SH Choi… - Pancreas, 2007 - journals.lww.com
Objectives: The purpose of this study was to screen for genes related to lymph node
metastasis by comparing the differences in the expression profile between pancreatic …

A direct comparison of patients with hereditary and sporadic pancreatic neuroendocrine tumors: evaluation of clinical course, prognostic factors and genotype …

P Soczomski, B Jurecka-Lubieniecka… - Frontiers in …, 2021 - frontiersin.org
Introduction Pancreatic neuroendocrine tumors (PNETs) in hereditary syndromes pose a
significant challenge to clinicians. The rarity of these syndromes and PNETs itself make it …

Grade increases in gastroenteropancreatic neuroendocrine tumor metastases compared to the primary tumor

F Grillo, M Albertelli, MP Brisigotti, T Borra… - …, 2016 - karger.com
Abstract Background/Aim: The neuroendocrine tumor (NET) proliferation-based grading
system (ENETS/WHO) for gastroenteropancreatic (GEP) tumors has proved reliable for …

Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer

B Lawrence, C Blenkiron, K Parker, P Tsai… - NPJ genomic …, 2018 - nature.com
Pancreatic neuroendocrine tumors (pNETs) are uncommon cancers arising from pancreatic
islet cells. Here we report the analysis of gene mutation, copy number, and RNA expression …

Well-differentiated pancreatic neuroendocrine tumors: from genetics to therapy

RF De Wilde, BH Edil, RH Hruban… - Nature Reviews …, 2012 - nature.com
Well-differentiated pancreatic neuroendocrine tumors (PanNETs) comprise∼ 1–3% of
pancreatic neoplasms. Although long considered as reasonably benign lesions, PanNETs …

Pancreatic neuroendocrine neoplasms: basic biology, current treatment strategies and prospects for the future

A Ohmoto, H Rokutan, S Yachida - International journal of molecular …, 2017 - mdpi.com
Pancreatic neuroendocrine neoplasms (pNENs) are rare tumors accounting for only 1%–2%
of all pancreatic tumors. pNENs are pathologically heterogeneous and are categorized into …

Prognostic criteria in nonfunctioning pancreatic endocrine tumours

S La Rosa, C Capella, F Sessa, C Riva, BE Leone… - Virchows Archiv, 1996 - Springer
To identify prognostic subgroups among nonfunctioning (nonsyndromic) pancreatic
endocrine tumours, a series of 61 tumours were analysed systematically for macroscopic …

High-grade progression confers poor survival in pancreatic neuroendocrine tumors

J Botling, A Lamarca, D Bajic, O Norlén… - …, 2020 - karger.com
Introduction: Little is known about how pancreatic neuroendocrine tumors (PanNETs) evolve
over time and if changes toward a more aggressive biology correlate with prognosis. The …

Endocrine tumors of the pancreas: Ki-67 immunoreactivity on paraffin sections is an independent predictor for malignancy: a comparative study with proliferating-cell …

G Pelosi, E Bresaola, G Bogina, F Pasini, S Rodella… - Human pathology, 1996 - Elsevier
Prediction for malignancy of pancreatic endocrine tumors (PET) is often a formidable
challenge for the pathologist. The authors evaluated the role of the proliferative activity and …

[HTML][HTML] Assessment of pancreatic neuroendocrine tumor cytologic genotype diversity to guide personalized medicine using a custom gastroenteropancreatic next …

FC Gleeson, JS Voss, BR Kipp, SE Kerr… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Recent genetic studies have highlighted that alterations in MEN1, chromatin
remodeling genes, and mammalian target of rapamycin (mTOR) pathway genes are the …