[HTML][HTML] Icariin modulates carrageenan-induced acute inflammation through HO-1/Nrf2 and NF-kB signaling pathways

NA El-Shitany, BG Eid - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Cellular inflammation has been recognized as the leading factor in numerous diseases,
causing either cell death, organ-specific damage, or genesis of different cancers. Icariin, a …

Impact of Icariin and its derivatives on inflammatory diseases and relevant signaling pathways

Z Luo, J Dong, J Wu - International immunopharmacology, 2022 - Elsevier
Herba Epimedii is a famous herb collected from China and Korea. It has been used for
impotency, osteoporosis, and amnestic treatment for thousands of years. Icariin, a typical …

Icariin attenuates LPS-induced acute inflammatory responses: Involvement of PI3K/Akt and NF-κB signaling pathway

CQ Xu, BJ Liu, JF Wu, YC Xu, XH Duan, YX Cao… - European journal of …, 2010 - Elsevier
This study aimed to investigate the mechanism underlying the attenuation of LPS-induced
lung inflammation by icariin in vivo and in vitro. The anti-inflammatory effects of icariin on …

Chrysoeriol ameliorates TPA-induced acute skin inflammation in mice and inhibits NF-κB and STAT3 pathways

JY Wu, YJ Chen, L Bai, YX Liu, XQ Fu, PL Zhu, JK Li… - Phytomedicine, 2020 - Elsevier
Background Chrysoeriol is a flavone found in diverse dietary and medicinal herbs such as
Lonicerae Japonicae Flos (the dried flower bud or newly bloomed flower of Lonicera …

[HTML][HTML] Anti-inflammatory and immunoregulatory effects of icariin and icaritin

Z Bi, W Zhang, X Yan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Inflammation and immunity dysregulation have received widespread attention in recent
years due to their occurrence in the pathophysiology of many conditions. In this regard …

Icariin inhibits TNF-α/IFN-γ induced inflammatory response via inhibition of the substance P and p38-MAPK signaling pathway in human keratinocytes

L Kong, J Liu, J Wang, Q Luo, H Zhang, B Liu… - International …, 2015 - Elsevier
Pro-inflammatory cytokines play a crucial role in the etiology of atopic dermatitis. We
demonstrated that Herba Epimedii has anti-inflammatory potential in an atopic dermatitis …

Icariin inhibits the inflammation through down-regulating NF-κB/HIF-2α signal pathways in chondrocytes

P Wang, Q Meng, W Wang, S Zhang, X Xiong… - Bioscience …, 2020 - portlandpress.com
Articular cartilage injury or defect is a common disease and is mainly characterized by
cartilage degradation because of chondrocyte inflammation. By now, there are no effective …

Zingerone mitigates carrageenan-induced inflammation through antioxidant and anti-inflammatory activities

S Mehrzadi, H Khalili, I Fatemi, A Malayeri… - Inflammation, 2021 - Springer
Inflammation is the body's response against various pathogens and has a critical role in
numerous diseases. Zingerone (Zing), a bioactive substance derived from ginger root, has a …

[HTML][HTML] Caffeic acid and ellagic acid ameliorate adjuvant-induced arthritis in rats via targeting inflammatory signals, chitinase-3-like protein-1 and angiogenesis

EM Fikry, AM Gad, AH Eid, HH Arab - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory arthropathy that principally attacks the
joints. The present study aimed to explore the potential anti-arthritic effects of caffeic acid …

An overview on immunoregulatory and anti-inflammatory properties of chrysin and flavonoids substances

M Zeinali, SA Rezaee, H Hosseinzadeh - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Inflammation and the pro-inflammatory cytokines are associated with numerous chronic
diseases. Studies suggest that flavonoids, plant polyphenolic compound derivatives from …