Discontinued disease-modifying therapies for Alzheimer's disease: status and future perspectives
BP Imbimbo, M Lozupone, M Watling… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Alzheimer's disease (AD) is the main cause of dementia and represents a huge
burden for patients, carers, and healthcare systems. Extensive efforts for over 20 years have …
burden for patients, carers, and healthcare systems. Extensive efforts for over 20 years have …
Recent trends in treatment strategies for Alzheimer's disease and the challenges: A topical advancement
N Liu, X Liang, Y Chen, L Xie - Ageing Research Reviews, 2024 - Elsevier
Alzheimer's Disease (AD) is an irreversible and progressive neurological disease that has
affected at least 50 million people around the globe. Considering the severity of the disease …
affected at least 50 million people around the globe. Considering the severity of the disease …
Should drug discovery scientists still embrace the amyloid hypothesis for Alzheimer's disease or should they be looking elsewhere?
BP Imbimbo, S Ippati, M Watling - Expert Opinion on Drug …, 2020 - Taylor & Francis
ABSTRACT Introduction Alzheimer's Disease (AD) represents a large and growing
challenge to patients, carers and healthcare systems, yet extensive efforts to develop …
challenge to patients, carers and healthcare systems, yet extensive efforts to develop …
Current perspectives on pharmacotherapy of Alzheimer's disease
K Chopra, S Misra, A Kuhad - Expert opinion on pharmacotherapy, 2011 - Taylor & Francis
Introduction: Alzheimer's disease (AD) is a daunting public health threat that has prompted
the scientific community's ongoing efforts to decipher the underlying disease mechanism …
the scientific community's ongoing efforts to decipher the underlying disease mechanism …
Update on Alzheimer's disease therapeutics
MS Rafii - Reviews on recent clinical trials, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Clinically, it is
characterized by progressive cognitive impairment and the emergence of neuropsychiatric …
characterized by progressive cognitive impairment and the emergence of neuropsychiatric …
Drug treatments in development for Alzheimer's disease
MC Woodward - Journal of Pharmacy Practice and Research, 2012 - Wiley Online Library
New therapies are needed to combat the symptoms and underlying disease processes in
the dementias. A rapid increase in our understanding of the risk factors for dementia and the …
the dementias. A rapid increase in our understanding of the risk factors for dementia and the …
Emerging treatments for Alzheimer's disease for non-amyloid and non-tau targets
Introduction: The number of people with dementia, including Alzheimer's disease, is growing
as a result of an ageing global population. Treatments available for AD only alleviate the …
as a result of an ageing global population. Treatments available for AD only alleviate the …
Clinical trials in Alzheimer's disease: a hurdle in the path of remedy
AE Oxford, ES Stewart, TT Rohn - International Journal of …, 2020 - Wiley Online Library
Human clinical trials seek to ameliorate the disease states and symptomatic progression of
illnesses that, as of yet, are largely untreatable according to clinical standards. Ideally …
illnesses that, as of yet, are largely untreatable according to clinical standards. Ideally …
[HTML][HTML] New treatment strategies for Alzheimer's disease: is there a hope?
I Aprahamian, F Stella, OV Forlenza - Indian Journal of Medical …, 2013 - journals.lww.com
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease, and
corresponds to the most common cause of dementia worldwide. Although not fully …
corresponds to the most common cause of dementia worldwide. Although not fully …
Therapeutic approaches to Alzheimer's disease
HW Klafki, M Staufenbiel, J Kornhuber, J Wiltfang - Brain, 2006 - academic.oup.com
Alzheimer's disease is an age-related progressive neurodegenerative disorder with an
enormous unmet medical need. It is the most common form of dementia affecting∼ 5% of …
enormous unmet medical need. It is the most common form of dementia affecting∼ 5% of …