Neuroinflammation is the key factor associated with the progression of Parkinson's disease
(PD). Pramipexole (PPX) has anti-inflammatory and antioxidant properties. This study …

Pain is one of the principal non-motor symptoms of Parkinson's disease (PD), negatively
impacting the patient's quality of life. This study aimed to demonstrate whether an effective …

Inflammation is one of the pathogenic processes in Parkinson's disease (PD). Dopamine
receptor agonist pramipexole (PPX) is extensively used for PD treatment in clinics. A number …

Pramipexole (PPX) is a common drug for the treatment of Parkinson's disease. However, the
mechanism allows PPX in the progression of Parkinson's disease remains largely unknown …

Objective: Fasudil, a Rho kinase inhibitor, has neuroprotection in the 1-methyl-4-phenyl-1, 2,
3, 6-tetrahydropyridine (MPTP)-based Parkinson's disease (PD). This study aims to …

Our previous study showed that α-Cyperone inhibited the inflammatory response triggered
by activated microglia and protected dopaminergic neuron in in vitro cell model of …

Background Parkinson's disease (PD) is a common neurodegenerative disease with a rapid
increase in incidence in recent years. Existing treatments cannot slow or stop the …

Background Pramipexole is the dopamine receptor agonist commonly used for treatment of
PD, the effect of which on immunity played an important role in pathological process is also …

Paeonol is a major phenolic compound of the Chinese herb, Cortex Moutan, and is known
for its antioxidant, anti-inflammatory and antitumor properties. The present study was …

Objectives This study aimed to explore the neuroprotective effects of paeoniflorin on
oxidative stress and apoptosis in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) …