The lengths of G-tracts and their connecting loop sequences determine G-quadruplex
folding and stability. Complete understanding of the sequence–structure relationships …

A G-rich sequence was designed to allow folding into either a stable parallel or hybrid-type
topology. With the parent sequence featuring coexisting species, various related sequences …

DNA G-quadruplexes are essential motifs in molecular biology performing a wide range of
functions enabled by their unique and diverse structures. In this study, we focus on the …

Conspectus G-quadruplexes (G4s) are distinctive four-stranded DNA or RNA structures
found within cells that are thought to play functional roles in gene regulation and …

The complex folding energy landscape of DNA G-quadruplexes leads to numerous
conformations for this functionally important class of noncanonical DNA structures. A new …

The G-triplex is a kind of DNA structure formed by G-rich sequences. Previous studies have
shown that it is an intermediate for the folding of G-quadruplex and has an antiparallel …

The folding kinetics is an important parameter affecting the relevance of DNA and RNA G-
quadruplex (G4) structures in biological processes. Previous studies of the G4 folding …

Abstract G-quadruplexes (G4) are nucleic acid conformations of guanine-rich sequences, in
which guanines are arranged in the square-planar G-tetrads, stacked on one another. G4 …

Guanine-rich repeat sequences are known to adopt diverse G-quadruplex (G4) topologies.
Determining the unfolding rates of individual G4 species is challenging due to the …

DNA guanine-quadruplexes (G-quadruplexes) are unique DNA structures formed by
guanine-rich sequences. The loop regions of G-quadruplexes play key roles in stability and …