Using machine learning to identify proteomic and metabolomic signatures of stroke in atrial fibrillation
F Zhang, Y Zhang, Q Zhou, Y Shi, X Gao, S Zhai… - Computers in Biology …, 2024 - Elsevier
Atrial fibrillation (AF) is a common cardiac arrhythmia, with stroke being its most detrimental
comorbidity. The exact mechanism of AF related stroke (AFS) still needs to be explored. In …
comorbidity. The exact mechanism of AF related stroke (AFS) still needs to be explored. In …
Comprehensive metabolomic and proteomic analyses reveal candidate biomarkers and related metabolic networks in atrial fibrillation
J Zhou, L Sun, L Chen, S Liu, L Zhong, M Cui - Metabolomics, 2019 - Springer
Introduction Atrial fibrillation (AF) is an abnormal heart rhythm characterized by an irregular
beating of the atria and is associated with an increased risk of heart failure, dementia, and …
beating of the atria and is associated with an increased risk of heart failure, dementia, and …
Metabolomic and proteomic analyses of persistent valvular atrial fibrillation and non-valvular atrial fibrillation
B Hu, W Ge, Y Wang, X Zhang, T Li, H Cui… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) is an abnormal heart rhythm related to an increased risk of heart failure,
dementia, and stroke. The distinction between valvular and non-valvular AF remains a …
dementia, and stroke. The distinction between valvular and non-valvular AF remains a …
Combined metabolic, phenomic and genomic data to prioritize atrial fibrillation-related metabolites
ZT Yan, JM Huang, WL Luo… - Experimental and …, 2019 - spandidos-publications.com
Metabolites in atrial fibrillation (AF) were characterized to further explore the molecular
mechanisms of AF by integrating metabolic, phenomic and genomic data. Gene expression …
mechanisms of AF by integrating metabolic, phenomic and genomic data. Gene expression …
Integration of proteomic and metabolomic characterization in atrial fibrillation-induced heart failure
H Zhang, L Wang, D Yin, Q Zhou, L Lv, Z Dong, Y Shi - BMC genomics, 2022 - Springer
Background The exact mechanism of atrial fibrillation (AF)-induced heart failure (HF)
remains unclear. Proteomics and metabolomics were integrated to in this study, as to …
remains unclear. Proteomics and metabolomics were integrated to in this study, as to …
Comprehensive metabolomic characterization of atrial fibrillation
C Lu, C Liu, D Mei, M Yu, J Bai, X Bao… - Frontiers in …, 2022 - frontiersin.org
Background Using human humoral metabolomic profiling, we can discover the diagnostic
biomarkers and pathogenesis of disease. The specific characterization of atrial fibrillation …
biomarkers and pathogenesis of disease. The specific characterization of atrial fibrillation …
Proteomic profiles of patients with atrial fibrillation provide candidate biomarkers for diagnosis
WY Zhong, H Yang, YL Wang, Y Yang, CF Guo… - International Journal of …, 2021 - Elsevier
Background Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide with an
increasing risk of heart failure, stroke, and thromboembolic events. Currently distinct …
increasing risk of heart failure, stroke, and thromboembolic events. Currently distinct …
Multiple targets related to mitochondrial function unveiled by metabolomics and proteomics profiles of hearts from atrial fibrillation patients
W Liu, B Hu, Y Wang, X Zhang, M Zhu, Y Shi… - Frontiers in …, 2023 - frontiersin.org
Background: The prominent mitochondrial metabolic changes of the atrium reportedly have
significant impact on electrical signals and structural remodeling which play important roles …
significant impact on electrical signals and structural remodeling which play important roles …
Bioinformatic gene analysis for potential biomarkers and therapeutic targets of atrial fibrillation-related stroke
R Zou, D Zhang, L Lv, W Shi, Z Song, B Yi, B Lai… - Journal of translational …, 2019 - Springer
Background Atrial fibrillation (AF) is one of the most prevalent sustained arrhythmias,
however, epidemiological data may understate its actual prevalence. Meanwhile, AF is …
however, epidemiological data may understate its actual prevalence. Meanwhile, AF is …
Identification of co-expressed genes between atrial fibrillation and stroke
Y Zhang, L Meng, M Hao, J Yang, T Zou - Frontiers in neurology, 2020 - frontiersin.org
Atrial fibrillation (AF) increases the risk of ischemic stroke and systemic arterial embolism.
However, the risk factors or predictors of stroke in AF patients have not been clarified …
However, the risk factors or predictors of stroke in AF patients have not been clarified …