Ribosome-inactivating proteins (RIPs) are toxic because they bind to 28S rRNA and
depurinate a specific adenine residue from the α-sarcin/ricin loop (SRL), thereby inhibiting …

Ricin produced by the castor bean plant and Shiga toxins produced by pathogenic
Escherichia coli (STEC) and Shigella dysenteriae are type II ribosome inactivating proteins …

The plant toxin ricin is highly toxic for mammalian cells and is of concern for bioterrorism.
Ricin belongs to a family of functionally related toxins, collectively referred to as ribosome …

Ribosome-inactivating proteins (RIPs) are N-glycosidases, which depurinate a specific
adenine residue in the conserved α-sarcin/ricin loop (α-SRL) of rRNA. This loop is important …

Ribosome-inactivating proteins (RIPs) are potent toxins that inactivate ribosomes by
catalytically removing a specific adenine from the α-sarcin/ricin loop (SRL) of the large …

Ribosome‐inactivating proteins (RIPs) are toxic proteins with N‐glycosidase activity. RIPs
exert their action by removing a specific purine from 28S rRNA, thereby, irreversibly …

Shiga-like toxins and ricin are ribosome-inactivating proteins (RIPs) that are lethal to
mammals and pose a global health threat. No clinical vaccines or therapeutics currently …

α-Sarcin and ricin represent two structurally and mechanistically distinct families of site-
specific enzymes that block translation by irreversibly modifying the sarcin/ricin loop (SRL) of …

Ribosome inhibiting proteins, RIPs, are a widespread family of toxic enzymes. Ricin is a
plant toxin used as a poison and biological warfare agent; shiga toxin is a homologue …

Ricin is a member of the ubiquitous ribosome‐inactivating protein (RIP) family of toxins. The
Centers for Disease Control and Prevention (CDC) classify ricin and related toxins as …