[HTML][HTML] Grainyhead-like 2 promotes tumor growth and is associated with poor prognosis in colorectal cancer
Y Quan, M Xu, P Cui, M Ye, B Zhuang, Z Min - Journal of Cancer, 2015 - ncbi.nlm.nih.gov
GRHL2 was implicated in regulating cancer development. Our previous study demonstrated
that knockdown GRHL2 in colorectal cancer (CRC) cells inhibited cell proliferation by …
that knockdown GRHL2 in colorectal cancer (CRC) cells inhibited cell proliferation by …
Downregulation of GRHL2 inhibits the proliferation of colorectal cancer cells by targeting ZEB1
Y Quan, R Jin, A Huang, H Zhao, B Feng… - Cancer biology & …, 2014 - Taylor & Francis
Previous reports have associated GRHL2 with tumor progression. However, the biological
role of GRHL2 in human colorectal cancer (CRC) has not been explored. We examined the …
role of GRHL2 in human colorectal cancer (CRC) has not been explored. We examined the …
Knockdown of GRHL2 inhibited proliferation and induced apoptosis of colorectal cancer by suppressing the PI3K/Akt pathway
F Hu, Z He, C Sun, D Rong - Gene, 2019 - Elsevier
Abstract Grainyhead-like 2 (GRHL2) transcription factor is implicated in many types of
cancers. However, the role of GRHL2 in colorectal cancer (CRC) has not been fully …
cancers. However, the role of GRHL2 in colorectal cancer (CRC) has not been fully …
GRHL2 inhibits colorectal cancer progression and metastasis via oppressing epithelial-mesenchymal transition
Z Yang, D Wu, Y Chen, Z Min, Y Quan - Cancer biology & therapy, 2019 - Taylor & Francis
Our previous study has demonstrated that knockdown of Grainyhead-like 2 (GRHL2) in
colorectal cancer (CRC) cells inhibited cell proliferation by targeting ZEB1. This study aimed …
colorectal cancer (CRC) cells inhibited cell proliferation by targeting ZEB1. This study aimed …
Expression and role of grainyhead-like 2 in gastric cancer
J Xiang, X Fu, W Ran, X Chen, Z Hang, H Mao… - Medical oncology, 2013 - Springer
The aim of this study was to evaluate the expression and role of Grhl2 in gastric cancer.
Immunohistochemistry was performed to explore the expression of Grhl2 in gastric cancer …
Immunohistochemistry was performed to explore the expression of Grhl2 in gastric cancer …
[HTML][HTML] Expression of transcription factor grainyhead-like 2 is diminished in cervical cancer
LA Torres-Reyes, L Alvarado-Ruiz… - … Journal of Clinical …, 2014 - ncbi.nlm.nih.gov
The transcription factor grainyhead-like 2 (GRHL2) is evolutionarily conserved in many
different species, and is involved in morphogenesis, epithelial differentiation, and the control …
different species, and is involved in morphogenesis, epithelial differentiation, and the control …
[HTML][HTML] Grainyhead-like 2 as a double-edged sword in development and cancer
J He, C Feng, H Zhu, S Wu, P Jin… - American journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Grainyhead-like 2 (GRHL2), one of the three homologs of Drosophila grainyhead,
contributes to epithelial morphogenesis and differentiation. Dysregulation of GRHL2 has …
contributes to epithelial morphogenesis and differentiation. Dysregulation of GRHL2 has …
Grainyhead-like 2 regulates epithelial plasticity and stemness in oral cancer cells
W Chen, JK Yi, T Shimane, S Mehrazarin… - …, 2016 - academic.oup.com
Abstract Grainyhead-like 2 (GRHL2) is one of the three mammalian homologues of
Drosophila Grainyhead involved in epithelial morphogenesis. We recently showed that …
Drosophila Grainyhead involved in epithelial morphogenesis. We recently showed that …
[HTML][HTML] EGFR-ERK induced activation of GRHL1 promotes cell cycle progression by up-regulating cell cycle related genes in lung cancer
Y He, M Gan, Y Wang, T Huang, J Wang, T Han… - Cell Death & …, 2021 - nature.com
Abstract Grainyhead-like 1 (GRHL1) is a transcription factor involved in embryonic
development. However, little is known about the biological functions of GRHL1 in cancer. In …
development. However, little is known about the biological functions of GRHL1 in cancer. In …
Diverse expression patterns of the EMT suppressor grainyhead‐like 2 (GRHL 2) in normal and tumour tissues
S Riethdorf, S Frey, S Santjer… - … Journal of Cancer, 2016 - Wiley Online Library
The transcription factor grainyhead‐like 2 (GRHL2) plays a crucial role in various
developmental processes. Although GRHL2 recently has attracted considerable interest in …
developmental processes. Although GRHL2 recently has attracted considerable interest in …