Altered response dynamics and increased population correlation to tonal stimuli embedded in noise in aging auditory cortex

K Shilling-Scrivo, J Mittelstadt… - Journal of …, 2021 - Soc Neuroscience
Age-related hearing loss (presbycusis) is a chronic health condition that affects one-third of
the world population. One hallmark of presbycusis is a difficulty hearing in noisy …

Environmental noise degrades hippocampus-related learning and memory

Y Zhang, M Zhu, Y Sun, B Tang… - Proceedings of the …, 2021 - National Acad Sciences
The neural mechanisms underlying the impacts of noise on nonauditory function, particularly
learning and memory, remain largely unknown. Here, we demonstrate that rats exposed …

Noise trauma impairs neurogenesis in the rat hippocampus

KS Kraus, S Mitra, Z Jimenez, S Hinduja, D Ding… - Neuroscience, 2010 - Elsevier
The hippocampus, a major site of neurogenesis in the adult brain, plays an important role in
memory. Based on earlier observations where exposure to high-intensity noise not only …

[HTML][HTML] Sensorineural hearing loss may lead to dementia-related pathological changes in hippocampal neurons

Y Shen, H Hu, C Fan, Q Wang, T Zou, B Ye… - Neurobiology of …, 2021 - Elsevier
Presbycusis contributes to cognitive decline and Alzheimer's disease. However, most
research in this area involves clinical observations and statistical modeling, and few studies …

Age-related cochlear synaptopathy: an early-onset contributor to auditory functional decline

Y Sergeyenko, K Lall, MC Liberman… - Journal of …, 2013 - Soc Neuroscience
Aging listeners experience greater difficulty understanding speech in adverse listening
conditions and exhibit degraded temporal resolution, even when audiometric thresholds are …

Effects of loud noise on hippocampal and cerebellar-related behaviors.: Role of oxidative state

SL Urán, LG Cáceres, LR Guelman - Brain research, 2010 - Elsevier
Living organisms are exposed to potentially hazardous noise levels coming from the
environment. Besides the direct effect on hearing, extra-auditory noise-associated effects …

Noise damage accelerates auditory aging and tinnitus: a Canadian population-based study

Z Jafari, T Copps, G Hole, BE Kolb… - Otology & …, 2020 - journals.lww.com
Objective: Age-related hearing loss (ARHL) is the third most challenging disability in older
adults. Noise is a known modifiable risk factor of ARHL, which can drive adverse health …

Acute and long‐term effects of noise exposure on the neuronal spontaneous activity in cochlear nucleus and inferior colliculus brain slices

M Gröschel, J Ryll, R Götze, A Ernst… - BioMed research …, 2014 - Wiley Online Library
Noise exposure leads to an immediate hearing loss and is followed by a long‐lasting
permanent threshold shift, accompanied by changes of cellular properties within the central …

Insula and amygdala atrophy are associated with functional impairment in subjects with presbycusis

C Belkhiria, RC Vergara, S San Martin… - Frontiers in aging …, 2020 - frontiersin.org
Hearing loss is an important risk factor for dementia. However, the mechanisms that relate
these disorders are still unknown. As a proxy of this relationship, we studied the structural …

The role of glia in the peripheral and central auditory system following noise overexposure: contribution of TNF-α and IL-1β to the pathogenesis of hearing loss

V Fuentes-Santamaría, JC Alvarado… - Frontiers in …, 2017 - frontiersin.org
Repeated noise exposure induces inflammation and cellular adaptations in the peripheral
and central auditory system resulting in pathophysiology of hearing loss. In this study, we …