[HTML][HTML] Antidepressant effect of EGCG through the inhibition of hippocampal neuroinflammation in chronic unpredictable mild stress-induced depression rat model

J Wang, S Xu, X Chen, L Wang, J Li, G Li… - Journal of Functional …, 2020 - Elsevier
In our study, a chronic unpredictable mild stress-induced depression rat model was
constructed then the antidepressant effects and mechanisms of Epigallocatechin-3-O-gallate …

Effect of epigallocatechin-3-gallate on stress-induced depression in a mouse model: Role of interleukin-1β and brain-derived neurotrophic factor

NE Abdelmeguid, TM Hammad… - Neurochemical …, 2022 - Springer
Abstract Epigallocatechin 3-gallate (EGCG) is a natural polyphenolic antioxidant in green
tea leaves with well-known health-promoting properties. However, the influence of EGCG on …

Effects of epigallocatechin-3-gallate on behavioral impairments induced by psychological stress in rats

WQ Chen, XL Zhao, DL Wang, ST Li… - Experimental …, 2010 - journals.sagepub.com
This study was conducted to explore the effects of epigallocatechin-3-gallate (EGCG) on
cognitive performances in psychological stress rats. An animal model of psychological stress …

Protective effect of epigallocatechin‐3‐gallate against neuroinflammation and anxiety‐like behavior in a rat model of myocardial infarction

J Wang, P Li, T Qin, D Sun, X Zhao… - Brain and behavior, 2020 - Wiley Online Library
Objective Individuals who experience myocardial infarction (MI) often experience anxiety.
Green tea has potent antioxidative properties and, epigallocatechin‐3‐gallate (EGCG) …

(−)‐Epigallocatechin gallate alleviates chronic unpredictable mild stress‐induced depressive symptoms in mice by regulating the mTOR autophagy pathway and …

Y Zhang, H Wu, C Xu, S Li, Y Hu, Z Zhang… - Food Science & …, 2024 - Wiley Online Library
Depression is a global public health issue that is widely studied due to the large number of
people it affects and its serious consequences. Clinical studies have shown that regular tea …

Effects of EGCG on depression-related behavior and serotonin concentration in a rat model of chronic unpredictable mild stress

G Li, J Yang, X Wang, C Zhou, X Zheng, W Lin - Food & function, 2020 - pubs.rsc.org
The aim of this study is to examine the antidepressant-like effect of EGCG and get deeper
insights into implications of modulating serotonin (5-HT) in the colon and brain. A total of 24 …

Antidepressive effects of kaempferol mediated by reduction of oxidative stress, proinflammatory cytokines and up-regulation of AKT/β-catenin cascade

W Gao, W Wang, Y Peng, Z Deng - Metabolic Brain Disease, 2019 - Springer
Kaempferol (KFL), the major constituent of various fruits and vegetables, could attenuate
oxidaitve stress and inflammation. The aims of the present study were to explore the …

Resveratrol ameliorates chronic unpredictable mild stress-induced depression-like behavior: involvement of the HPA axis, inflammatory markers, BDNF, and Wnt/β …

XH Yang, SQ Song, Y Xu - Neuropsychiatric disease and treatment, 2017 - Taylor & Francis
Classic antidepressant drugs are modestly effective across the population and most are
associated with intolerable side effects. Recently, numerous lines of evidence suggest that …

Resveratrol exerts a protective effect in chronic unpredictable mild stress–induced depressive-like behavior: involvement of the AKT/GSK3β signaling pathway in …

J Shen, C Qu, L Xu, H Sun, J Zhang - Psychopharmacology, 2019 - Springer
Background Chronic unpredictable mild stress (CUMS) is an important contributing factor for
depression with inflammatory response alteration, neuron apoptosis, and decreased …

Naringenin and apigenin ameliorates corticosterone-induced depressive behaviors

L Zhang, RR Lu, RH Xu, HH Wang, WS Feng… - Heliyon, 2023 - cell.com
Background Depression is a common kind of mental illness, and it becomes the main health
burden in the world. Purpose The aim of this study was to investigate the antidepressant …