Bacteria encounter a myriad of stresses in their natural environments, including, for
pathogens, their hosts. These stresses elicit a variety of specific and highly regulated …

Bacteria can be adapted to adverse and detrimental conditions that induce general and
specific responses to DNA damage as well as acid, heat, cold, starvation, oxidative …

Bacteria encounter a myriad of potentially growth-compromising conditions in nature and in
hosts of pathogenic bacteria. These 'stresses' typically elicit protective and/or adaptive …

Gain new insight on utilizing bacterial stress responses to better combat bacterial infection
with antibiotics and improve biotechnology.• Reviews the vast number of new findings that …

This study aimed at elucidating the physiological basis of bacterial antibiotic tolerance. By
use of a combined phenotypic and gene knockout approach, exogenous nutrient …

A better understanding of the impact of antibiotics on bacteria is required to increase the
efficiency of antibiotic treatments and to slow the emergence of resistance. Using …

Bacterial Stress Responses: What Doesn't Kill Them Can Make Them Stronger | PLOS Biology
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The alarming spread of bacterial strains exhibiting resistance to current antibiotic therapies
necessitates that we elucidate the specific genetic and biochemical responses underlying …

Several promising strategies based on combining or cycling different antibiotics have been
proposed to increase efficacy and counteract resistance evolution, but we still lack a deep …

Bacteria are well known for their extremely high adaptability in stressful environments. The
clinical relevance of this property is clearly illustrated by the ever-decreasing efficacy of …