The c-MYC protein participates in energy-consuming processes such as proliferation and
ribosome biosynthesis, and its expression is often dysregulated in human cancers. Cancer …

Metabolic reprogramming supports cancer cells' demands for rapid proliferation and growth.
Previous work shows that oncogenes, such as MYC, hypoxia-inducible factor 1 (HIF1), have …

The processes of cellular growth regulation and cellular metabolism are closely interrelated.
The c-Myc oncogene is a “master regulator” which controls many aspects of both of these …

The perils and promises of inspiratory hyperoxia (IH) in oncology are still controversial,
especially for patients with lung cancer. Increasing evidence shows that hyperoxia exposure …

Transcription factors of the MYC family are deregulated in the majority of all human cancers.
Oncogenic levels of MYC reprogram cellular metabolism, a hallmark of cancer development …

The MYC proto-oncoproteins including c-MYC, MYCN and MYCL exert their functions as
heterodimers with MAX, which in turn binds to E-box sequences at target promoters to …

The c-myc proto-oncogene is rapidly activated by serum and regulates genes involved in
metabolism and cell cycle progression. This gene is thereby uniquely poised to coordinate …

The MYC proto-oncogene is frequently activated in human cancers through a variety of
mechanisms. Its deregulated expression, unconstrained by inactivation of key checkpoints …

Cancer cells generate large amounts of lactate derived from glucose regardless of the
available oxygen level. Cancer cells finely control ATP synthesis by modulating the uptake …

The c‐Myc proto‐oncogene is activated in more than half of all human cancers. However,
the precise regulation of c‐Myc protein stability is unknown. Here, we show that the lnc RNA …