Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …

Mitochondria are at the center of cellular energy metabolism and regulate cell life and death.
The cell biological aspect of mitochondria, especially mitochondrial dynamics, has drawn …

Myocardial infarction (MI) is the irreversible death of cardiomyocyte secondary to prolonged
lack of oxygen or fresh blood supply. Historically considered as merely cardiomyocyte …

Tobacco smoking is a major risk factor for cardiovascular disease and hypertension. It is
associated with the oxidative stress and induces metabolic reprogramming, altering …

Mitochondria are critical for cardiomyocyte survival and maintenance of normal cardiac
function. However, changes in the extra-or intracellular environments during stress can …

Cardiovascular disease (CVD) is a leading cause of mortality worldwide. Proper
mitochondrial function is necessary in tissues and organs that are of high energy demand …

Background—Coronary atherosclerotic disease remains the leading cause of death in the
Western world. Although the exact sequence of events in this process is controversial …

Cardiovascular disease is a major leading cause of morbidity and mortality in the United
States and elsewhere. Alterations in mitochondrial function are increasingly being …

Significance: Diabetes is an important risk factor for the development of heart failure (HF).
Given the increasing prevalence of diabetes in the population, strategies are needed to …

Mitochondria have long been known to play a critical role in maintaining the bioenergetic
status of cells under physiological conditions. It was also recognized early in mitochondrial …