Why sex hormones matter for neuroscience: A very short review on sex, sex hormones, and functional brain asymmetries

M Hausmann - Journal of neuroscience research, 2017 - Wiley Online Library
Biological sex and sex hormones are known to affect functional cerebral asymmetries
(FCAs). Men are generally more lateralized than women. The effect size of this sex …

Minireview: sex chromosomes and brain sexual differentiation

AP Arnold, J Xu, W Grisham, X Chen, YH Kim… - …, 2004 - academic.oup.com
The brains of males and females differ, not only in regions specialized for reproduction, but
also in other regions (controlling cognition, for example) where sex differences are not …

Sexual neurosteroids and synaptic plasticity in the hippocampus

L Fester, GM Rune - Brain research, 2015 - Elsevier
Abstract Sexual neurosteroids (SN), namely 17β-estradiol (E2) and 5α-dehydrotestosterone
(DHT), are synthesized in the hippocampus, where they induce circuit modifications by …

[HTML][HTML] Sex hormones and gender role relate to gray matter volumes in sexually dimorphic brain areas

B Pletzer - Frontiers in neuroscience, 2019 - frontiersin.org
The present study investigates the relationship of circulating sex hormone levels and gender
role to gray matter volumes in sexually dimorphic brain areas and explores, whether these …

Genetic and epigenetic underpinnings of sex differences in the brain and in neurological and psychiatric disease susceptibility

IA Qureshi, MF Mehler - Progress in brain research, 2010 - Elsevier
There are numerous examples of sex differences in brain and behavior and in susceptibility
to a broad range of brain diseases. For example, gene expression is sexually dimorphic …

Stress experienced in utero reduces sexual dichotomies in neurogenesis, microenvironment, and cell death in the adult rat hippocampus

CD Mandyam, EF Crawford, AJ Eisch… - Developmental …, 2008 - Wiley Online Library
Hippocampal function and plasticity differ with gender, but the regulatory mechanisms
underlying sex differences remain elusive and may be established early in life. The present …

[HTML][HTML] Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

CA Mangold, B Wronowski, M Du, DR Masser… - Journal of …, 2017 - Springer
Background The necessity of including both males and females in molecular neuroscience
research is now well understood. However, there is relatively limited basic biological data on …

[HTML][HTML] In-vivo dynamics of the human hippocampus across the menstrual cycle

C Barth, CJ Steele, K Mueller, VP Rekkas, K Arélin… - Scientific reports, 2016 - nature.com
Sex hormones fluctuate during the menstrual cycle. Evidence from animal studies suggests
similar subtle fluctuations in hippocampal structure, predominantly linked to estrogen …

It is not all hormones: alternative explanations for sexual differentiation of the brain

W Davies, LS Wilkinson - Brain research, 2006 - Elsevier
Males and females of many species differ with regard to neurodevelopment, ongoing brain
function and behavior. For many years, it was assumed that these differences primarily …

Neuroscience and sex/gender: Looking back and forward

M Hines - Journal of Neuroscience, 2020 - Soc Neuroscience
) reported that treating pregnant guinea pigs with testosterone had enduring effects on the
sex-related behavior of their female offspring. Since then, similar enduring effects of early …